Biothermodynamics, Part C

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2011
ISBN13: 9780123812681
Rubricering
Elsevier Science e druk, 2011 9780123812681
Onderdeel van serie Methods in Enzymology
€ 207,25
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In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. Biothermodynamics, Part C presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.

The use of thermodynamics in biological research is used as an “energy book-keeping system.” While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance?

As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well.

Specificaties

ISBN13:9780123812681
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<ol> <li>Measurement and Analysis of Equilibrium Binding Titrations: A beginner’s guide</li> <p>Dorothy Beckett</p> <p> <li>Macromolecular Competition Titration Method: Accessing Thermodynamics of the Unmodified Macromolecule – Ligand Interactions Through Spectroscopic Titrations of Fluorescent Analogs</li> <p>Wlodzimierz Bujalowski and Maria J. Jezewska</p> <p> <li>Analysis of PKR-RNA interactions by sedimentation velocity</li> <p>C. Jason Wong, Katherine Launer-Felty and James L. Cole</p> <p> <li>Structural and Thermodynamic Analysis of PDZ/Ligand Interactions</li> <p>Tyson R. Shepherd and Ernesto J. Fuentes</p> <p> <li>Thermodynamic analysis of metal ion-induced protein assembly</li> <p>Andrew B. Herr and Deborah G. Conrady</p> <p> <li>Thermodynamic Dissection of Colicin Interactions</li> <p>Nicholas G Housden and Colin Kleanthous</p> <p> <li>Energetics of Src homology domain interactions in receptor tyrosine kinase-mediated signaling</li> <p>John E. Ladbury and Stefan T. Arold</p> <p> <li>Structural and Functional Energetic Linkages in Allosteric Regulation of Muscle Pyruvate Kinase</li> <p>J. Ching Lee and Petr Herman</p> <p> <li>Analysis of Free Energy versus Temperature Curves in Protein Folding and Macromolecular Interactions</li> <p>Vince J. LiCata and Chin-Chi Liu</p> <p> <li>Application of the Sequential n-Step Kinetic Mechanism to Polypeptide Translocases</li> <p>Aaron L. Lucius<SUB>, </SUB>Justin M. Miller and Burki Rajendar</p> <p> <li>A Coupled Equilibrium Approach to Study Nucleosome Thermodynamics</li> <p>Andrew J. Andrews and Karolin Luger</p> <p> <li>Quantitative methods for measuring DNA flexibility in vitro and in vivo</li> <p>Justin P. Peters, Nicole Becker, Emily M. Rueter, Zeljko Bajzer, Jason D. Kahna and L. James Maher</p> <p> <li>A Thermodynamic Approach for the Targeting of Nucleic Acid Structures Using Their Complementary Single Strands</li> <p>Hui-Ting Lee, Caroline Carr, Hollie Siebler, Lela Waters, Irine Khutsishvili, Fany Iseka, Brian Domack, Chris M. Olsen, and Luis Marky</p> <p> <li>Thermodynamics of Biological Processes</li> <p>Hernan G. Garcia, Jane Kondev, Nigel Orme, Julie Theriot and Rob Phillips</p> <p> <li>Protein stability in the presence of co-solutes</li> <p>Luis Marcelo F. Holthauzen, Matthew Auton, Mikhail Sineva and Jorg Rosgen</p> <p> <li>Small Angle X-ray Scattering Studies of Peptide-Lipid Interactions using the Mouse Paneth Cell α-Defensin Cryptdin-4</li> <p>Abhijit Mishra, Kenneth P. Tai, Nathan W. Schmidt, André J. Ouellette and Gerard C. L. Wong</p> <p> <li>Synergy of molecular dynamics and isothermal titration calorimetry in studies of allostery</li> <p>Rebecca Strawn, Thomas Stockner, Milan Melichercik, Lihua Jin, Wei-Feng Xue, Jannette Carey and Rüdiger Ettrich</p> <p> <li>Using tryptophan fluorescence to measure the stability of membrane proteins folded in liposomes</li> <p>C. Preston Moon1 and Karen G. Fleming</p> <p> <li>Non-B Conformations of CAG Repeats Using 2-aminopurine</li> <p>Natalya N. Degtyareva and Jeffrey T. Petty</p> <p> <li>Disulfide bond-mediated passenger domain stalling as a structural probe of autotransporter outer membrane secretion in vivo</li> <p>Jonathan P. Renn & Patricia L. Clark</p> <p> <li>Strategies for the Thermodynamic Characterization of Linked Binding/Local Folding Reactions Within the Native State: Application to the LID Domain of Adenylate Kinase from Escherichia coli</li> </ol> <p>Travis P. Schrank, W. Austin Elam, Jing Li and Vincent J. Hilser</p>
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        Biothermodynamics, Part C