Biomedical Hydrogels

<p>Part I: Processing of hydrogels</p> <p>Chapter 1: Hydrogel swelling behavior and its biomedical applications</p> <p>Abstract:</p> <p>1.1 Basics of hydrogels</p> <p>1.2 Swelling of hydrogels: water diffusion into hydrogels</p> <p>1.3 Stimulus-responsive hydrogels</p> <p>1.4 Examples of environment-sensitive hydrogels</p> <p>1.5 Future trends</p> <p>Chapter 2: Superabsorbent cellulose-based hydrogels for biomedical applications</p> <p>Abstract:</p> <p>2.1 Introduction</p> <p>2.2 Cellulose-based hydrogels and crosslinking strategies</p> <p>2.3 Hydrogel properties and thermodynamics</p> <p>2.4 Applications</p> <p>2.5 Conclusions</p> <p>Chapter 3: Synthesis of hydrogels for biomedical applications: control of structure and properties</p> <p>Abstract:</p> <p>3.1 Introduction</p> <p>3.2 Cross-linking of high molecular weight polymers</p> <p>3.3 Copolymerization with multi-functional monomers</p> <p>3.4 Multiphase hydrogels</p> <p>3.5 Functional hydrogels</p> <p>3.6 Conclusion</p> <p>Chapter 4: Processing and fabrication technologies for biomedical hydrogels</p> <p>Abstract:</p> <p>4.1 Introduction</p> <p>4.2 Applications</p> <p>4.3 Gelation</p> <p>4.4 Physical crosslinking</p> <p>4.5 Photopolymerization and photopatterning</p> <p>4.6 Stereolithography</p> <p>4.7 Two-photon laser scanning photolithography</p> <p>4.8 Processing of multicomponent hydrogels</p> <p>4.9 Future trends</p> <p>4.10 Acknowledgements</p> <p>Chapter 5: Regulation of novel biomedical hydrogel products</p> <p>Abstract:</p> <p>5.1 Introduction</p> <p>5.2 Regulatory jurisdictions</p> <p>5.3 Regulatory frameworks</p> <p>5.4 Risk-based device classification</p> <p>5.5 Non-clinical testing</p> <p>5.6 Clinical data and studies</p> <p>5.7 Marketing authorization processes</p> <p>5.8 Quality system requirements</p> <p>5.9 Post-market requirements</p> <p>5.10 Future trends</p> <p>5.11 Sources of further information and advice</p> <p>Part II: Applications of hydrogels</p> <p>Chapter 6: Spinal disc implants using hydrogels</p> <p>Abstract:</p> <p>6.1 Introduction</p> <p>6.2 Intervertebral disc</p> <p>6.3 Disc implant</p> <p>6.4 Conclusion</p> <p>Chapter 7: Hydrogels for intraocular lenses and other ophthalmic prostheses</p> <p>Abstract:</p> <p>7.1 Introduction</p> <p>7.2 Intraocular lenses</p> <p>7.3 Vitreous substitutes</p> <p>7.4 Tissue adhesives</p> <p>7.5 Conclusions</p> <p>7.5 Acknowledgements</p> <p>Chapter 8: Cartilage replacement implants using hydrogels</p> <p>Abstract:</p> <p>8.1 Introduction</p> <p>8.2 Historical background in cartilage repair and injury: existing therapies</p> <p>8.3 First and second generation tissue engineering</p> <p>8.4 Third generation tissue engineering</p> <p>8.5 Future trends</p> <p>Chapter 9: Hydrogels for wound healing applications</p> <p>Abstract:</p> <p>9.1 Introduction</p> <p>9.2 Requirements of an ideal wound care system</p> <p>9.3 Hydrogels for wound healing applications</p> <p>9.4 Natural hydrogels for wound healing applications</p> <p>9.5 Synthetic and other hydrogels for wound healing applications</p> <p>9.6 Commercial dressings</p> <p>9.7 Future trends</p> <p>9.8 Conclusion</p> <p>9.10 Appendix: list of abbreviations</p> <p>Chapter 10: Imaging hydrogel implants in situ</p> <p>Abstract:</p> <p>10.1 Introduction</p> <p>10.2 Rationale for imaging implants in situ</p> <p>10.3 Imaging modalities and their advantages and disadvantages for the in situ imaging of hydrogel implants</p> <p>10.4 Challenges of imaging in situ</p> <p>10.5 Contrast enhancement</p> <p>10.6 Characterization of implants (in vitro and in vivo)</p> <p>10.7 Characterization of in vivo healing</p> <p>10.8 Conclusions</p> <p>10.9 Sources of further information and advice</p> <p>Index</p>