<p>1. Introduction</p> <p>References</p> <p>2. Evolution of phycobiliproteins</p> <p>References </p> 3. Structural and functional significance <p></p> <p>3.1 Introduction</p> <p>3.2 Occurrence and diversity </p> <p>3.3 Ultra structure </p> <p>3.4 Chromophore integrity and energy pathway</p> <p>References</p> <p>4. Gene manipulation and biosynthesis of phycobiliproteins</p> <p>4.1 Introduction</p> <p>4.2 Biosynthesis mechanism</p> 4.3 Gene manipulation and transformation<p></p> <p>4.4 Chromatic adaptation</p> 4.5 Signal transduction<p></p> <p>References</p> <p>5. Stress response of phycobiliproteins</p> 5.1 Abiotic stress<p></p> <p>References</p> <p>6. Advances in production technology< </p><p>6.1 Introduction</p> <p>6.2 Strategies and types of cultivation </p> 6.3 Utilization<p></p> <p>References</p> <p>7. Advances and strategies of purification technology</p> <p>7.1 Introduction</p> <p>7.2 Techniques of purification </p> 7.3 Yield and purity index<p></p> <p>7.4 Market and cost benefit analysis</p> <p>References</p> <p>8. Biotechnological applications </p> <p>8.1 Introduction</p> 8.2 Neutraceuticals and natural food colorants<p></p> <p>8.3 Pharmaceuticals and fluorescence probe </p> 8.4 Cosmetics <p></p> <p>References</p> <p>9. Role in therapeutic sciences </p> 9.1 Introduction<p></p> <p>9.2 Therapeutic behavior in various disease</p> 9.3 Molecular view of therapeutic science <p></p> <p>9.4 Emerging technology</p> <p>References </p> 10. Future development and challenges <p></p> <p> References</p>