Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders

Novel Strategies for Research and Treatment

Specificaties
Paperback, 564 blz. | Engels
Springer Netherlands | 0e druk, 2010
ISBN13: 9789048177387
Rubricering
Springer Netherlands 0e druk, 2010 9789048177387
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This book provides an up-to-date overview of the role of neurosteroids and neuroactive steroids in the regulation of brain processes and neuropsychiatric disorders. It addresses the neurosteroid function in brain development and plasticity, in both the normal and the pathological brain. It also suggests possible therapeutic approaches to the use of natural occurring or sinthetic neurosteroids. The contributors suggest that neuroactive steroids could have a role in clinical practice.

Specificaties

ISBN13:9789048177387
Taal:Engels
Bindwijze:paperback
Aantal pagina's:564
Uitgever:Springer Netherlands
Druk:0

Inhoudsopgave

Neuroactive Steroids and Brain Functions.- Neurosteroid: Molecular Mechanisms of Action on the GABAA Receptor.- Steroid Metabolism in Glial Cells.- Involvement of Neuroactive Steroids in Hippocampal Disorders: Lessons from Animal Models.- Estrogen Modulation of Visceral Nociception.- Neuroactive Steroids: Effects on Cognitive Functions.- Estrogen, Cholinergic System and Cognition.- Local Production of Estrogen and its Rapid Modulatory Action on Synaptic Plasticity.- Effects of Estradiol and DHEA on Morphological Synaptic Plasticity.- Pregnane Steroids and Short-Term Neural Plasticity.- Steroidogenesis and Neuroplasticity in the Songbird Brain.- Dehydroepiandrosterone, as Endogenous Inhibitor of Neuronal Cell Apoptosis: Potential Therapeutic Implications in Neurodegenerative Diseases.- DHEA and DHEA-S, and their Functions in the Brain and Adrenal Medulla.- Neurosteroids in the Aging Brain.- Neuroactive Steroids and Neuropsychiatric Disorders.- Dehydroepiandrosterone and Pregnenolone Alterations in Schizophrenia.- Neurosteroids in Cortical Development and the Etiology of Schizophrenia.- Neurosteroid Perturbation and Neuropsychiatric Symptoms in Schizophrenia: From the Mechanisms to the Treatment.- Dehydroepiandrosterone Administration in Treating Medical and Neuropsychiatric Disorders.- Allopregnanolone and Pregnenolone Alterations Following Pharmacological Agents in Rodents and Clinic Populations.- Reconsidering Classifi cations of Depression Syndromes: Lessons from Neuroactive Steroids and Evolutionary Sciences.- Neuroactive Steroids in Brain and Relevance to Mood.- The Role of Neuroactive Steroids in Anxiety Disorders.- The Role of Midbrain 3?,5?-THP in Mediating Exploration, Anxiety, Social, and Reproductive Behavior.- The Role of Progesterone and its Metabolites in Premenstrual Disorders of Affect.- Neurosteroid Derangement in Women Diagnosed with Eating Disorders.- Neurosteroids in Alcohol and Substance Use.- The Role of Neurosteroids in Development of Pediatric Psychopathology.

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        Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders