,

Annual Reports in Combinatorial Chemistry and Molecular Diversity

Specificaties
Paperback, 174 blz. | Engels
Springer Netherlands | 0e druk, 2010
ISBN13: 9789048152278
Rubricering
Springer Netherlands 0e druk, 2010 9789048152278
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Combinatorial chemistry and molecular diversity approaches to scientific and novel product R & D have exploded in the 1990s. For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research.
The second volume in this series includes contributions on methods, solid phases, purification, analysis, carbohydrates, patent strategies and tactics, diversity profiling and combinatorial series design, and finishes with a survey of chemical libraries yielding biologically active agents and a compendium of solid phase chemistry publications. Each contribution is prepared by a recognized expert resulting in a high quality account of the recent advances in the field.

Specificaties

ISBN13:9789048152278
Taal:Engels
Bindwijze:paperback
Aantal pagina's:174
Uitgever:Springer Netherlands
Druk:0

Inhoudsopgave

Solution-phase combinatorial chemistry.- New developments in solid phase synthesis supports.- Recent advances in solid phase synthesis.- Purification of combinatorial libraries.- Analytical methods for quality control of combinatorial libraries.- Accessing carbohydrate-based combinatorial libraries through solid phase and solution phase approaches.- Patent strategies in molecular diversity.- Patent tactics in molecular diversity: Things that get around, come around (Or: There are always exceptions to the rule).- Advances in diversity profiling and combinatorial series design.- Comprehensive survey of chemical libraries yielding enzyme inhibitors, receptor agonists and antagonists, and other biologically active agents: 1992 through 1997.- A compendium of solid-phase chemistry publications.- Author Index.

Rubrieken

Populaire producten

    Personen

      Trefwoorden

        Annual Reports in Combinatorial Chemistry and Molecular Diversity