Jeffrey M. Weinberg,
Robin Buchholz
Birkhäuser Basel
2006e druk, 2006
9783764372484
TNF-alpha Inhibitors
Specificaties
Gebonden, 133 blz.
|
Engels
Birkhäuser Basel |
2006e druk, 2006
ISBN13: 9783764372484
Rubricering
Onderdeel van serie
Milestones in Drug Therapy
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
This volume provides a comprehensive overview of the development, pharmacology, efficacy, and safety of the currently available TNF-alpha inhibitors. It is the first volume that summarizes this material for all available TNF-alpha inhibitors. Elevated levels of TNF-alpha have been demonstrated in Crohn's disease, psoriasis, psoriatic arthritis, and rheumatoid arthritis, suggesting a role for TNF-alpha in their pathogenesis. The most recent preclinical and clinical data is presented in this book.
Specificaties
ISBN13:9783764372484
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:133
Uitgever:Birkhäuser Basel
Druk:2006
Inhoudsopgave
Preface.- Introduction to TNF/Pathophysiology of TNF.- History of development of TNF inhibitors.- Pharmacology of TNF inhibitors.- Etanercept in rheumatology.- Etanercept in dermatology and off-label use.- Infliximab in rheumatology.- Infliximab in dermatology, gastroenterology and off-label use.- Adalimumab in rheumatology.- Adalimumab in dermatology.- A review of the safety of the tumor necrosis inhibitors infliximab, etanercept, and adalimumab.