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The Biology of Germinal Centers in Lymphoid Tissue

Specificaties
Paperback, 241 blz. | Engels
Springer Berlin Heidelberg | 0e druk, 2013
ISBN13: 9783662131435
Rubricering
Springer Berlin Heidelberg 0e druk, 2013 9783662131435
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.

Specificaties

ISBN13:9783662131435
Taal:Engels
Bindwijze:paperback
Aantal pagina's:241
Uitgever:Springer Berlin Heidelberg
Druk:0

Inhoudsopgave

1. Overview of Germinal Center Function and Structure in Normal and Genetically Engineered Mice.- 2. The Germinal Center Reaction: Influence of FDC Function in Normal, Aged, and Retrovirus Infected Hosts.- 3. T and B Lymphocytes in Germinal Centers.- 4. Somatic Hypermutation of Immunoglobulin Genes.- 5. Germinal Center Derived Lymphomas in Humans and Mice.- Color Figures.

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        The Biology of Germinal Centers in Lymphoid Tissue