1 Cell Volume Regulatory Mechanisms – An Overview.- 1 Introduction.- 2 Mechanisms of Regulatory Cell Volume Decrease (RVD).- 3 Mechanisms of Regulatory Cell Volume Increase (RVI).- 4 Factors Activating or Modifying Cell Volume Regulatory Mechanisms.- 5 Conclusions.- References.- 2 Cell Volume and Hepatic Metabolism.- 1 Introduction.- 2 Cell Volume Control in Liver.- 3 Modulation of Hepatic Metabolism by Cell Volume.- 4 Cell Volume and Bile Formation.- 5 Role of Cell Volume in Hormone Action.- 6 Signalling Systems.- 7 Perspective.- References.- 3 Volume Regulation in Transporting Epithelia.- 1 Introduction.- 2 Mechanisms of Epithelial Cell Volume Regulation.- 3 Intestinal Transport and Volume Regulation.- 4 Control of Renal Cell Volume: The Renal Medulla Role of Organic Solutes in Cell Volume Regulation.- 5 Regulation of Liver Cell Volume.- 6 Conclusion.- References.- 4 Cell Volume and Stimulus-Secretion Coupling.- 1 General Aspects of Secretion.- 2 Fluid Secretion in Exocrine Acinar Cells.- 3 Volume Changes During Exocrine Secretion.- 4 Volume Counterregulatory Mechanisms During Exocrine Secretion.- 5 Volume Changes During Endocrine Secretion.- 6 Possible Regulatory Role of the Cell Volume for Renin Secretion.- 7 Summary.- References.- 5 Cell Volume Regulation and Vascular Endothelial Function.- 1 Introduction.- 2 Regulatory Volume Decrease in Endothelium.- 3 Regulatory Volume Increase.- 4 Cell Volume Regulation and Endothelial Function.- References.- 6 Effects of Swelling on Glial Cell Function.- 1 Astroglial Swelling in Situ – Contribution to Pathology.- 2 Methods for Studying Glial Swelling.- 3 Mechanisms of Astrocytic Swelling.- 4 Functional Consequences of Glial Swelling.- 5 Conclusions.- References.- 7 Cell Volume Regulation: Intracellular Transmission.- 1Introduction.- 2 Principal Ion Transport Systems for Na+, K+ and Cl? Involved in Cell Volume Regulation.- 3 Activation Mechanisms for RVD.- 4 Activation Mechanism for RVI.- 5 Induction of Organic Osmolyte Transport Systems.- 6 Biological Role of Volume Regulation.- References.- 8 Regulation of Volume-Modulating Ion Transport Systems by Growth Promoters.- 1 Introduction.- 2 Effect of Growth Promoters on Na+/H+ Exchange.- 3 Effect of Growth Promoters on Na/K/CI Cotransport.- 4 Concluding Remarks.- References.- 9 The Regulation of Organelle Function Through Changes in Their Volume.- 1 Introduction.- 2 The Regulation of Mitochondrial Volume.- 3 Changes in the Mitochondrial Matrix Volume as a Mechanism of Hormone Signal Transduction Across the Liver Mitochondrial Membrane.- 4 Regulation of Mitochondrial Volume in Other Tissues.- 5 Swelling of Mitochondria Occurs in Pathological States.- References.