Achim Kramer,
Martha Merrow
Springer Berlin Heidelberg
e druk, 2015
9783642448539
Circadian Clocks
Specificaties
Paperback, blz.
|
Engels
Springer Berlin Heidelberg |
e druk, 2015
ISBN13: 9783642448539
Rubricering
Onderdeel van serie
Handbook of Experimental Pharmacology
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
This book provides the reader with a contemporary and comprehensive overview about the molecular, cellular and system-wide principles of circadian clock regulation. Emphasis is placed on the importance of circadian clocks for the timing of therapeutic interventions.
Specificaties
ISBN13:9783642448539
Taal:Engels
Bindwijze:paperback
Uitgever:Springer Berlin Heidelberg
Inhoudsopgave
<p>Preface.- Part I.- Molecular and cellular basis of circadian clocks.- Molecular components of the mammalian circadian clock. The epigenetic language of circadian clocks. Peripheral circadian oscillators in mammals. The clock in the brain - neurons and networks in daily rhythms. Entrainment of circadian clocks.- Part II.- Circadian control of physiology and behavior.- Circadian clocks and metabolism. Circadian control of the immune system. The circadian control of sleep. Circadian clocks in mood-related behaviors.- Part III.- Chronopharmacology and chronotherapy.- The role of clock genes in pharmacology. Circadian timing in cancer treatments. Pharmacological modulators of the circadian clock as potential therapeutic drugs. The circadian system in shift-workers.- Part IV.- Systems biology of circadian clocks.- Mathematical modeling of circadian clocks. Transcriptional circuits in the mammalian circadian oscillator. Genome-wide analyses of circadian systems</p>.