Michael Karin
Springer Berlin Heidelberg
2011e druk, 2011
9783642160165
NF-kB in Health and Disease
Specificaties
Gebonden, 268 blz.
|
Engels
Springer Berlin Heidelberg |
2011e druk, 2011
ISBN13: 9783642160165
Rubricering
Onderdeel van serie
Current Topics in Microbiology and Immunology
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology—from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
Specificaties
ISBN13:9783642160165
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:268
Uitgever:Springer Berlin Heidelberg
Druk:2011
Inhoudsopgave
<p>Preface.- Understanding the Logic of IκB:NF-κB Regulation in Structural Terms.- NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogaster.- Specialized chromatin patterns in the control of inflammatory gene expression.- IKK regulation and human genetics.- Control of NF-κB activity by proteolysis.- NF-κB and Innate Immunity.- NF-κB and mucosal homeostasis.- IKK and NF-κB mediated functions in carcinogenesis.- Macrophages and NF-κB in Cancer.- NF-kappaB in liver cancer – the plot thickens.- NF-kappaB as a target for oncogenic viruses.- Inhibition of NF-κB signaling as a strategy in disease therapy.- Subject index</p>