Robert E. Rhoads
Springer Berlin Heidelberg
0e druk, 2010
9783642075056
Signaling Pathways for Translation
Stress, Calcium, and Rapamycin
Specificaties
Paperback, 178 blz.
|
Engels
Springer Berlin Heidelberg |
0e druk, 2010
ISBN13: 9783642075056
Rubricering
Onderdeel van serie
Progress in Molecular and Subcellular Biology
Verwachte levertijd ongeveer 8 werkdagen
Samenvatting
This volume presents the response of the eukaryotic translational apparatus to cellular stress and apoptosis, including kinases activated through both the ERK and stress-activated pathways. It further explores two agents that inhibit protein synthesis, calcium and the immunosuppressant rapamycin. Six chapters written by leading experts in the field provide both new data and comprehensive literature reviews. Both the regulation of initiation and elongation are discussed, and the mechanisms of apoptosis are related to changes in the protein synthesis machinery.
Specificaties
ISBN13:9783642075056
Taal:Engels
Bindwijze:paperback
Aantal pagina's:178
Uitgever:Springer Berlin Heidelberg
Druk:0
Inhoudsopgave
The Regulation of eIF4F During Cell Growth and Cell Death.- Regulation of the Activity of Eukaryotic Initiation Factors in Stressed Cells.- Initiation Factor eIF2? Phosphorylation in Stress Responses and Apoptosis.- Elongation Factor-2 Phosphorylation and the Regulation of Protein Synthesis by Calcium.- Phosphorylation of Mammalian eIF4E by Mnk1 and Mnk2: Tantalizing Prospects for a Role in Translation.- Control of Translation by the Target of Rapamycin Proteins.