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Histophysiology of the Obesity-Diabetes Syndrome in Sand Rats

Specificaties
Paperback, 95 blz. | Engels
Springer Berlin Heidelberg | e druk, 1994
ISBN13: 9783540579137
Rubricering
Springer Berlin Heidelberg e druk, 1994 9783540579137
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

The book gives a review of the state-of-the-art of recent investigations of the adipositas diabetes syndrome of sand rats kept under laboratory conditions and given various diet regimes. Measurements of specific activities and flux rates in carbohydrate and fat metabolism determined by different analytical methods in vitro and in vivo provide insights into the pathophysiology and pathobiochemistry of different forms of the diabetic syndrome which cannot be obtained in humans.

Specificaties

ISBN13:9783540579137
Taal:Engels
Bindwijze:paperback
Aantal pagina's:95
Uitgever:Springer Berlin Heidelberg

Inhoudsopgave

1 Introduction.- 1.1 Experimental Diabetes in the Sand Rat.- 1.1.1 Zoology.- 1.1.2 Physiological Characteristics.- 1.1.3 Types of Diet-Dependent Diabetes Development.- 2 Aims of the Study.- 2.1 Islet Cytology.- 2.2 Islets of Langerhans and Other Endocrine Organs in Diabetes Mellitus.- 3 Materials and Methods.- 3.1 Animal Housing.- 3.2 Animal Preparation and Investigation.- 3.2.1 In Vivo Experiments.- 3.2.2 In Vitro Experiments.- 3.2.3 Tissue Extraction and Analysis of Metabolites.- 3.3 Histological Methods.- 3.4 Cytochemical Methods.- 3.5 Electron Microscopy.- 3.6 Morphometry.- 3.6.1 Islets.- 3.6.2 Adenohypophysis.- 3.6.3 Adrenal Cortex.- 3.6.4 Thyroid.- 3.6.5 Gonads.- 3.6.6 Statistics.- 4 Islets.- 4.1 Islet Cytology.- 4.2 Innervation of the Pancreas and Islets of Langerhans.- 4.3 Islets of Langerhans in Diabetes Mellitus.- 4.4 Insulin Secretion of Islets of Langerhans.- 4.5 Insulin Resistance of Insulin-Sensitive Tissues.- 4.6 Influence of Stress on Insulin Resistance of Glucose Utilization and Hyperinsulinemia.- 5 Role of Other Endocrine Organs in Diabetes Mellitus.- 5.1 Adenohypophysis.- 5.2 Adrenal Cortex.- 5.3 Thyroid.- 5.4 Testicles.- 5.5 Ovaries.- 6 Conclusions.- 7 Summary.- References.

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        Histophysiology of the Obesity-Diabetes Syndrome in Sand Rats