Transplant International Official Journal of the European Society for Organ Transplantation

Kidney.- CSA/AZA, in the absence of prednisone, improves linear growth in renal transplanted children.- Late histopathological findings in renal allografts with four immunosuppressive regimens.- Flow cytometry evaluation of urinary sediment in renal transplantation.- Early diagnosis of kidney transplant rejection and cyclosporine nephrotoxicity by urine cytology.- Haemodynamic changes in human kidney allografts following administration of nifedipine: assessment with doppler spectrum analysis.- Cyclosporine renal cortical vasoconstriction measured by colour doppler imaging in kidney transplantation.- Monoclonal immunoglobulins in patients with renal transplants: characterization, evolution and risk factors.- Cytomegalovirus (CMV) excretion as a factor in the severity of CMV disease in kidney and simultaneous kidney and pancreas transplantation.- Prophylaxis of CMV disease by ganciclovir (DHPG) in seronegative recipients of renal allograft from seropositive donors.- Renal retransplantation in patients with HLA-antibodies.- Bilateral nephrectomy of the native kidneys reduces the incidence of arterial hypertension and erythrocytosis in kidney graft recipients treated with cyclosporine.- A logical basis for age matching in organ transplantation: studies of recipient renal function in relation to donor age.- Multicentre trial of ABO-incompatible kidney transplantation.- Should hepatitits-C virus antibody-positive donors be excluded from kidney donation?.- Cadaveric kidney donation beyond the age of 60 years - a comparative analysis of 1180 grafts from different donor age groups.- Antibodies against hepatitis C virus among renal transplant patients in Greece.- Value of panel reactive antibodies (PRA) as a guide to the treatment of hyperimmunized patients in renal transplantation.- Cyclosporin A (CsA) and azathioprine (AZA) combination in renal allografts with CsA nephrotoxicity.- Verapamil (VP) improves the outcome after renal transplantation (CRT).- DTPA renal scan assessment of renal allograft dysfunction in rats.- Renal retransplantation in Switzerland: poor HLA matching of first and subsequent allografts does not appear to affect overal graft survival.- Renal funtional reserve in kidney transplant recipients.- Nifedipine improves immediate, and 6-and 12-month graft function in cyclosporin A(CyA) treated renal allograft recipients.- Post-transplant haemoglobin levels and host kidney status.- Effect of ATG prophylaxis in sensitized and non-sensitized kidney graft recipients.- Ocular findings in patients with successful renal transplantation.- Influence of cyclosporin A (CyA) on renal handling of urate.- Erythrocytosis in renal allograft recipients. Benefit of staggered venous erythropoietin measurements.- In vitro FK506 kidney tubular cell toxicity.- FK506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells.- Early kidney transplantation may prevent aluminium-related bone disease.- Effect of prostaglandin E1 on graft function of kidneys from living related donors.- Renal transplantation in r-HuEPO-treated patients.- Long-term beneficial effects of azathioprine addition to ongoing cyclosporine-prednisone protocol in renal transplantation.- Protective effect of vasodilators in donors requiring pressor support.- The use of OKT3 in steroid-resistant rejections following cadaveric kidney transplantation.- Aging on the waiting list: should it be a further criterion for cadaver kidney allocation?.- Risk factors for development of panel reactive antibodies and their impact on kidney transplantation outcome.- Early or delayed onset of cyclosporine by sequential immunosuppression?.- Application of flow cytometry in clinical renal transplantation.- The course of HIV disease in renal allograft recipients.- The Japanese Interferon Study Group (JISG) has established the efficacy of human interferon-p for serious CMV pneumonitis in kidney recipients.- Factors affecting the long-term outcome following non-living kidney transplantation.- Is repeated mismatching at regrafting deleterious?.- Detrimental role of donor-recipient HLA-DQ5 and -DQ6 disparities on cadaver kidney graft survival.- CMV prophylaxis after renal transplantation with immunoglobulin or CMV-hyperimmunoglobulin - a prospective clinical trial.- Length of time on dialysis prior to renal transplantation is a critical factor affecting patient survival after allografting.- Donor conditions and graft survival-a retrospective study.- Clinical factors which influence the long-term survival of kidney allografts donated from haploidentical donors.- Glomerular hyperfiltration after unilateral nephrectomy in living kidney donors.- Liver.- The bile acid independent flow is reduced in the transplanted liver.- Quadruple immunosuppression including a new IL-2-receptor antibody and the incidence of infections after liver transplantation.- Should retransplantation still be considered for primary non-function after liver transplantation?.- Increased fibrinolysis in orthotopic but not in heterotopic liver transplantation: the role of the anhepatic phase.- A Pugh score of 8 adequately selects patients with parenchymal cirrhosis for liver transplantation.- Seroprevalence and outcome of hepatitis C in liver transplantation.- Somatomedin C (IGF I) plasma levels after orthotopic liver transplantation (OLT) in end-stage cirrhotic patients.- Adjuvant treatment with ursodeoxycholic acid reduces acute rejection after liver transplantation.- Cholestasis and kidney dysfunction in liver transplant patients reduces cyclosporine metabolite excretion.- Choledochoenterostomy with an anti-reflux mechanism.- Liver transplantation in hepatocellular carcinoma.- Technique of arterial anastomosis in liver transplantation, surgical management in routine situations and anatomical variations.- Biliary neopterin for differentiation between liver allograft rejection and viral graft infection.- Total hepatectomy and liver transplant for hepatocellular adenomatosis and focal nodular hyperplasia.- Liver transplantation for fulminant liverfailure in children.- The impact of the different severe infections on the outcome of liver transplantation. Astudy of 150 patients.- Hepatic support by hepatocyte transplantation in congenitally metabolic diseased rats.- Blood transfusion in orthotopic liver transplantation: six-year experience.- Liver transplantation for small HCC in cirrhosis.- Heart, Lung, Heart-Lung.- Results of acute heart retransplantation in Eurotransplant.- Right ventricular failure after heart transplantation: relationship with preoperative haemodynamic parameters.- Preoperative prostaglandin E1 treatment to prevent right ventricular failure after orthotopic heart transplantation.- Phenotype of endomyocardial biopsy-derived T-lymphocyte cultures and chronic rejection after heart transplantation.- The clinical value of ultrasonic tissue characterization in the management of heart transplant patients.- Coronary flow reserve is impaired early after cardiac transplantation.- Determinants of graft arteriosclerosis after heart transplantation.- Role of CMV pneumonia in the development of obliterative bronchiolitis in heart-lung and double-lung transplant recipients.- The use of allopurinol in the inhibition of obliterative bronchiolitis of the transplanted lung.- Evaluation of the International Society for Heart Transplantation (ISHT) grading of pulmonary rejection in 100 consecutive biopsies.- Coronary flow reserve and coronary occlusive disease.- Tricuspid valve insufficiency as a complication of endomyocardial biopsy.- Occurrence of lymphoproliferative disorder after heart transplantation is related to the total immunosuppressive load.- Pancreas, Islets, Small Bowel.- Perfusion imaging of pancreas allografts using technetium-99m hexamethyl propylene amine oxime.- Prospective analysis of pancreatic grafts with duplex-Doppler ultrasound: value of resistive index in the diagnosis of rejection.- Reperfusion injury of pancreas allografts: relation to islet cell function.- Isolation of pig pancreatic islets by a new method with hydraulic shaking: preliminary report.- The use of FK506 and RS61443 for reversal of small-bowel rejection.- Graft Monitoring.- Monitoring of cardiac graft recipients: comparison of in vivo activated, committed T lymphocytes in peripheral blood and in the graft.- Intercellular adhesion molecule 1 (ICAM-1) induction on hepatocytes is an early marker of acute liver allograft rejection.- Lung transplantation: pulmonary cell lysis mediated by alveolar mononuclear cells.- Nonspecific hemolytic effector of activated macrophages as activation marker of allograft rejection.- Relation of suppressor activity to lymphocyte subsets, in vitro IL-2R expression, and biopsy results in cardiac transplant patients.- ?2-Microglobulinuria as an early sign of cytomegalovirus infection following renal transplantation.- Xenografting.- Perfusion of rabbit hearts with human blood results in immediate graft thrombosis, a temporally distinct component of hyperacute rejection.- Allogeneic heart transplantation following xenogeneic bridging.- Activation of the alternative pathway of complement is an important component of hyperacute rejection of rabbit hearts by human blood.- Inhibition of rejection of hamster-to-rat heart xenografts.- Perfusion of rabbit hearts with pig blood results in complement mediated hyperacute xenograft rejection.- Antibody binding to endothelial and epithelial antigens triggers pig-to-rabbit xenograft rejection and its absence results in atypical complement deposition.- Preservation.- The influence of an improved preservation solution on prognostic factors for graft survival in pediatric liver transplantation.- Multivisceral cluster transplantation in the rat.- Reperfusion rather than storage injury predominates following long-term (48 h) cold storage of grafts in UW solution: studies with Carolina Rinse in transplanted rat liver.- Prolonged rat pancreas preservation using a solution with the combination of histidine and lactobionate.- The impact of liver preservation in HTK and UW solution on microcirculation after liver transplantation.- Myocardial preservation with the UW solution. First European results in clinical heart transplantation.- Protection by pentoxifylline against graft failure from storage injury after orthotopic rat livertransplantation with arterialization.- Pulmonary mechanics after cardio-pulmonary transplantation, an experimental study.- Simplified microvascular suture techniques for rat liver transplantation as a microsurgical model with arterial blood supply.- The second generation of Carolina Rinse, solution II, improves graft survival following orthotopic liver transplantation in the rat by preventing reperfusion injury.- Efficacy of PGI2 analog in preventing ischemia reperfusion damage of liver grafts from living donors.- Heart and lung preservation using a new solution; UCLA Formula.- Antagonisation of platelet activating factor- a new therapeutic concept for improvement of organ quality in lung preservation.- Usefulness of 31P-MRS as a method of evaluating the viability of preserved and transplanted rat liver.- Predictive value of liver tissue flow in assessment of the viability of liver grafts after extended preservation in pigs.- Successful 96-hour preservation of the canine pancreas.- The mechanism of action of the two-layer (Euro-Collins’ solution/perfluorochemical) cold storage method in canine pancreas preservation.- Improvement of liver preservation by the calcium channel blocker nisoldipine. An experimental study applying intravital microscopy to transplanted rat livers.- The calcium channel blocker nisoldipine minimizes the release of tumor necrosis factor and interleukin-6 following rat livertransplantation.- Comparison of HTK- and UW-solution for liver preservation tested in an orthotopic livertransplantation model in the pig.- Acomparison of histadine lactobionate solution with University of Wisconsin solution for rat liver and heart preservation.- The significant role of membrane stabilization in hypothermic cardioplegic cardiac preservation in a canine experimental model.- Kupffer cell and hepatocyte function in rat transplanted liver.- A newly developed hydroxyI radical scavenger, EPC-K1 can improve the survival of swine warm ischemia-damaged transplanted liver grafts.- Kidney procurement from non-heartbeating donors: transplantation results.- Apreliminary report of the HTK randomized multicenter study comparing kidney graft preservation with HTK and EuroCollins solutions.- The relationship between cause of death of the kidney donor and the presence of ischemic lesions in the kidney.- Immunosuppression.- High or low dose steroid therapy for acute renal transplant rejection after prophylactic OKT3 treatment: a prospective randomized study.- The risk of infection following OKT3 and antilymphocyte globulin treatment for renal transplant rejection: results of a single center prospectively randomized trial.- Prophylactic use of the IL-2 receptor-specific monoclonal antibody LO-Tact-1 with cyclosporin A and steroids in renal transplantation.- RS-61443: successful rescue therapy in refractory renal rejection.- Lymphoproliferative disorders developing after transplantation and their relation to simian T-cell leukemia virus infection.- Toxicology of FK506 in the cynomolgus monkey: a clinical, biochemical, and histopathological study.- CD4-specific monoclonal antibody can prolong cardiac allograft survival without T-cell depletion.- Prolongation of heart allograft survival in rats by interferon-specific antibodies and low dose cyclosporin A.- Effect of LS-2616 on the graft protection achieved by cyclosporin A, prednisolone, and 15-deoxyspergualin in heart-transplanted rats.- A randomized pilot study of cyclosporin G in renal transplantation.- Long-term immunosuppression after liver transplantation: are steroids necessary?.- Dosage of OKT3 independent of body weight: a mistake?.- Polyclonal versus monoclonal rejection prophylaxis after heart transplantation: a randomised study.- Pregnancy in kidney recipients under cyclosporine.- Low-dose combination therapy of DUP-785 and RS-61443 prolongs cardiac allograft survival in rats.- Immunomodulation of dog islets using a cocktail of monoclonal antibodies.- Prolongation of murine thyroid allografts by interleukin 2 (DAB486)-toxin and RS-61443.- The effects of nifedipine on cyclosporine nephrotoxicity in rats.- Cyclosporine-induced insulin release in rats is related to an increase in plasma lipid levels.- Cellular mechanisms: Induction of heart allograft survival in rats by 15-deoxyspergualin.- Control of humoral and cellular immunity-mediated accelerated heart allograft rejection in sensitized rats by low dose FK506 and splenectomy.- Prevention of lethal graft-versus-host disease by monoclonal antibody treatment in vivo.- Abdominal organ cluster transplantation in pigs and FK506.- Influence of hepatic dysfunction on cyclosporine metabolism in the pig.- FK506 and rapamycin: differential sensitivity of human, baboon, cynomolgus monkey dog and pig lymphocytes.- Ex vivo perfusion of canine pancreaticoduodenal allografts using class-II-specific monoclonal antibody delays the onset of acute rejection.- New immunosuppression with monoclonal antibody to intracellular adhesion molecule 1 (ICAM-1) in rat organ transplantation.- Japanese study of kidney transplantation: 1. Results of early phase II study.- Subclinical impairment of distal renal acidification induced by low-dose cyclosporin Atherapy.- Cyclosporin A has no impact on alterations of the lipid profile after renal transplantation.- Decrease of erythrocyte deformability in cyclosporine-treated renal transplant patients: correction with fish oil as well as corn oil.- Adjuvant treatment with ursodeoxycholic acid prevents acute rejection in rats receiving heart allografts.- RS-61443 reverses acute renal allograft rejection in dogs.- Gangliosides potentiate the immunosuppressive effects of cyclosporin A in rat skin allografts.- Rescue therapy for acute rejection using 15-deoxyspergualin (DSG) in combination with superoxide dismutase (SOD) on cardiac allografts in rats.- Japanese study of FK506 on kidney transplantation: 2. Follow-up study of FK 506-treated patients.- Insensitivity to cyclosporine may explain the HLA-DRw6 recipient effect.- An immunoglobulin-specific autoantibody occurring during alloimmunization suppresses the antibody response.- Prevention of cardiac allograft rejection by FK506 and rapamycin: assessment by histology and nuclear magnetic resonance.- New morphological changes induced by FK506 in a short period in the rat kidney and the effect of superoxide dismutase and OKY-046 on THEM: the relationship of FK506 nephrotoxicity to lipid peroxidation and change in production of thromboxane A2 in the kidney.- Immunology.- Is tolerance a prospective for clinical research?.- Will chronic rejection ever respond to treatment?.- DNA typing: an important step forward?.- The “rejection reaction” is not confined solely to the allograft.- Chronic rejection of rat aortic allografts: effect of inhibition of the thromboxane cascade.- Factors involved in peripheral T cell tolerance: the extent of clonal deletion or clonal anergy depends on the age of the tolerized lymphocytes.- Alio and auto crossmatches after transplantation.- Remarkable correlation between increased HLA-DQ antigen positive monocytes and prognosis of renal transplantation.- The influence of DR match of blood donor and recipient on the formation of T- and B-cell antibodies and on renal allograft outcome.- Success rate and impact of HLA matching on kidney graft survival in highly immunized recipients.- Flow cytometric crossmatching and outcome one year after renal transplantation.- Clinical relevance of soluble HLA and interaction of papain derived class I molecules with alloreactive CTL.- Lack of correlation between IgG T-lymphocyte flow cytometric crossmatches with primary renal allograft outcome.- Detection of latent human cytomegalovirus in organ tissue and the correlation with serological status.- Reactivity of renal transplant sera against a 17 kD mononuclear cell antigen.- Strength of HLA-A, HLA-B, and HLA-DR mismatches in relation to short- and long-term kidney graft survival.- Pretransplant serum lgG-anti-F(abé)2 g activity and kidney graft outcome: comparison of results obtained at two centers.- The impact of ischemic lesions in the donor kidney donor age, recipient age and HLA(A, B, C, DR, DQ) matching on clinical course after kidney grafting.- Non specific increased expression of class I major histocompatibility complex (MHC) antigens on rat liver grafts.- Intraoperative cytokines production during orthotopic liver transplantation.- Studies on the participation of different T cell subsets in rat liver allograft rejection.- Chronic renal allograft rejection: the significance of non-MHC alloantigens.- Lysis of heart endothelial cells from donor origin by cardiac graft infiltrating cells.- Expression of human decay accelerating factor or membrane cofactor protein genes on mouse cells inhibits lysis by human complement.- TNF staining of graft biopsy in renal transplantation.- Analysis of suppressor T cells induced by donor-specific transfusion (DST): establishment of a human T cell hybridoma producing an antigen-nonspecific suppressor factor.- Role of leukotrienes B4 and C4 in liver allograft rejection.- Suppression of human lymphocyte proliferation and cytotoxic T lymphocyte generation by a soluble factor derived from K562 cells.- FK506 ameliorates normothermic liver ischemia in rats by suppressing production of tumor necrosis factor.- Donor directed cytotoxicity of cardiac graft infiltrating cells during cytomegalovirus infection.- The influence of HLA-mismatches on phenotypic and functional characteristics of graft infiltrating lymphocytes after heart transplantation.- Kidney transplant monitoring by anti donor specific antibodies.- Cytokines in lethal graft-versus-host disease.- Absence of correlation between graft-versus-host associated immunosuppression and cytotoxic T cell activity in response to major histocompatibility antigens.- Rejection prophylaxis with interleukin-2 receptor antibody BT 563: mechanisms of action on human cells.- Hyaluronic acid accumulation; the mechanism behind graft rejection edema.- Expression of activation markers, HLA class II and IL-2R in acute vascular rejection of human renal allografts.- Cytokines.- T-cell receptor Vb gene usage by lymphocytes infiltrating human renal allografts.- Effects of interleukin 2 receptor b chain (P75)-specific monoclonal antibody on the generation of cytotoxic T lymphocytes and suppressor T cells in mixid lymphocyte culture.- Quality of Life.- Quality of life before and after liver transplantation: experiences with 7 patients with primary biliary cirrhosis in a 2-year follow-up.- Effect of kidney transplantation on quality of life measures.- Cognitive and behavioural status of paediatric patients 1 year after cardiac or cardiopulmonary transplantation.- The Donor Problem.- Perioperative hemodynamic heterogeneity of brain dead organ donors.- A reliable and safe way of shortening cadaver kidney ischemia time: prenephrectomy tissue typing using donor lymph node cells.- Assessment of costs to donor hospitals for organ transplantation.- Impact of donor age on living related donor kidney transplantation.