Robert E. Rhoads
Springer Berlin Heidelberg
2001e druk, 2001
9783540417101
Signaling Pathways for Translation
Stress, Calcium, and Rapamycin
Specificaties
Gebonden, 178 blz.
|
Engels
Springer Berlin Heidelberg |
2001e druk, 2001
ISBN13: 9783540417101
Rubricering
Onderdeel van serie
Progress in Molecular and Subcellular Biology
Levertijd ongeveer 8 werkdagen
Samenvatting
This volume presents the response of the eukaryotic translational apparatus to cellular stress and apoptosis, including kinases activated through both the ERK and stress-activated pathways. It further explores two agents that inhibit protein synthesis, calcium and the immunosuppressant rapamycin. Six chapters written by leading experts in the field provide both new data and comprehensive literature reviews. Both the regulation of initiation and elongation are discussed, and the mechanisms of apoptosis are related to changes in the protein synthesis machinery.
Specificaties
ISBN13:9783540417101
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:178
Uitgever:Springer Berlin Heidelberg
Druk:2001
Inhoudsopgave
The Regulation of eIF4F During Cell Growth and Cell Death.- Regulation of the Activity of Eukaryotic Initiation Factors in Stressed Cells.- Initiation Factor eIF2? Phosphorylation in Stress Responses and Apoptosis.- Elongation Factor-2 Phosphorylation and the Regulation of Protein Synthesis by Calcium.- Phosphorylation of Mammalian eIF4E by Mnk1 and Mnk2: Tantalizing Prospects for a Role in Translation.- Control of Translation by the Target of Rapamycin Proteins.