Ruud ter Meulen, Nikola Biller-Andorno, Christian Lenk, Reidar Lie - The ethical debate on Evidence-based Medicine. Introduction to the Volume Christine Sepers and Ruud ter Meulen - Regulating Health Care. The development of guidelines in medical practice and health policy Rein Vos, Rob Houtepen, Klasien Horstman - Evidence-based Medicine and Power Shifts in Health Care Systems Mariachiara Tallacchini - Beyond Legitimate Science: The Case for Policy-Related Science Franz Porzsolt and Heike Leonhardt-Huober - Teaching Evidence-based Medicine Frank Praetoriu - Evidence-based Medicine and Clinical Guidelines in Cardiology Promoting Science, Practice, or Bureaucracy? Fabrizio Fabris, Carla Scarafiotti, Barbara Maero - Are particular patients disadvantaged by EBM? Focus on frail elderly patients. Andreas Reis, Christian Lenk, Nikola Biller-Andorno - Evidence-based Medicine in Mental Health: Towards better and fairer treatment? Richard E. Ashcroft - Current Epistemological Problems in Evidence-based Medicine Rein Vos, Dick Willems, and Rob Houtepen - Coordinating the Norms and Values of Medical Research, Medical Practice and Patient Worlds - the Ethics of Evidence-based Medicine in 'Orphaned Fields of Medicine' Reidar K. Lie - Research Ethics and Evidence-based Medicine Heiner Raspe - Clinical evaluative research: which patients benefit, how and when? A contribution to a European discussion Alessandro Liberati and Paolo Vineis -Defining a proper background for discussing Evidence-based Medicine Wendy A. Rogers - Evidence-based Medicine and Equity: the Exclusion of Disadvantaged Groups Ole Frithjof Norheim - The Role of Formal Outcome Evaluations in Health Policy Making: A Normative Perspective Erik Nord - The Usefulness of Formal Outcome Evaluations in Health Policy Making: Looking for the Baby in the Bathwater Marion Danis - Evidence-based Medicine and Managed Care Rob Houtepen, Nikola Biller-Andorno, Donna Dickenson, Paolo Vineis, Reidar Lie, Ruud ter Meulen - Recommendations from the Evibase Project Christine Sepers & Ruud ter Meulen - Selected bibliography on ethics and EBM