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TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease

Specificaties
Paperback, blz. | Engels
Springer International Publishing | e druk, 2018
ISBN13: 9783319884530
Rubricering
Springer International Publishing e druk, 2018 9783319884530
€ 192,99
Levertijd ongeveer 8 werkdagen

Samenvatting

This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development. It begins by discussing the structure/function of TCTP, before exploring its role in different species ranging from plants to Drosophila and covering fields such as development, the cytoskeleton, cell division, DNA fragility and apoptosis.

In turn, the book’s final section is devoted to the role of TCTP in disease, namely asthma and diverse cancers, and ultimately as a target for the treatment of malignancies. What is the common denominator between all these processes and why is TCTP necessary in order for them to occur, even in the worst case such as cancer? The book seeks to provide meaningful answers to this and other key questions. Presenting a broad and revealing view on the topic, it offers an informative guide for scientists and students alike.

Specificaties

ISBN13:9783319884530
Taal:Engels
Bindwijze:paperback
Uitgever:Springer International Publishing

Inhoudsopgave

<div>1. Introduction: role of TCTP from the stem cell to cell death and cancer</div><div>Adam Telerman and Robert Amson (atelerman@gmail.com)</div><div><br/></div><div><div>2. Structural insights into TCTP and its interactions with ligands and proteins.</div><div>Nadine Assrir a, Florian Malarda, Ewen Lescop (Ewen.LESCOP@cnrs.fr)</div><div><br/></div><div><div>3. Crystal structure of the protein complex between TCTP and bcl-xl</div><div>Jean Cavarelli (cava@igbmc.fr)</div></div><div><br/></div><div><div>4. Phylogenetic conservation and Structure-Function analysis of TCTP</div><div>Beatriz Xoconostle-Cázares and Roberto Ruiz-Medrano (rmedrano@cinvestav.mx)</div></div><div><br/></div><div><div>5. The Translational Controlled Tumour Protein TCTP: Biological Functions and</div><div>Regulation</div><div>Ulrich-Axel Bommer (ubommer@uow.edu.au)</div></div><div><br/></div><div><div>6. Current understanding of the TCTP interactome</div><div>Siting Li and Feng Ge (gefeng@ihb.ac.cn)</div><br/></div>7. </div>Role and fate of TCTP in protein degradative pathways<div>Michel Vidal  (michel.vidal@umontpellier.fr)</div><div><br/></div><div><div>8. Roles of the Translationally Controlled Tumor Protein (TCTP) in plant development</div><div>BETSCH Léo, SAVARIN Julie, BENDAHMANE Mohammed, SZECSI Judit (mohammed.bendahmane@ens-lyon.fr)</div></div><div><br/></div><div><div>9. Function of Translationally controlled tumor protein in organ growth: Lessons from</div><div>Drosophila studies</div><div>Kwang-Wook Choi1*, Sung-Tae Hong1 and Thao Phuong Le1 (kchoi100@kaist.ac.kr)</div></div><div><br/></div><div><div>10. Function of TCTP in Spider venom</div><div>Andrea Senff -Ribeiro (senffribeiro@gmail.com)</div><div><br/></div><div><div>11. TCTP in cell division</div><div>Malgorzata Kloc and Jacek Kubiac (jacek.kubiak@univ-rennes1.fr)</div></div><div><br/></div><div><div>12. Tctp in Neuronal Circuitry Assembly</div><div>Cláudio Gouveia Roque and Christine E. Holt (cag2230@cumc.columbia.ed)</div>&</div></div>amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;<br/><div> 13. TCTP and the apoptotic machinery</div><div>David W. Andrews (david.andrews.lab@gmail.com)</div><div><br/></div><div><div>14. TCTP as a pharmacologic target</div><div>Thomas Efferth (efferth@uni-mainz.de)</div></div><div><br/></div><div><div>15. TCTP has a crucial role in the different stages of Prostate Cancer malignant progression </div></div><div>Virginie Baylot, Sara Karaki and Palma Rocchi (palma.rocchi@inserm.fr)<br/></div><div><br/></div><div>16. TCTP: a therapeutic target in cancer<br/></div><div>Robert Amson and Adam Telerman (amson @noos.fr)<br/></div><div><br/></div><div><div>17. History of Histamine Releasing Factor (HRF)/Translationally Controlled Tumor Protein (TCTP) including a Potential Therapeutic Target in Asthma and Allergy</div><div>Susan M. MacDonald (smacdona@jhmi.edu)</div></div><div><br/></div><div>Conclusions and perspectives</div><div><br/></div><div><br/></div><div><br/></div>/div>
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        TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease