Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy

New Perspectives and Opportunities

Specificaties
Paperback, blz. | Engels
Springer International Publishing | e druk, 2018
ISBN13: 9783319818801
Rubricering
Springer International Publishing e druk, 2018 9783319818801
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews.
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.

Specificaties

ISBN13:9783319818801
Taal:Engels
Bindwijze:paperback
Uitgever:Springer International Publishing

Inhoudsopgave

Foreword.- Preface.- 1. Molecular Cell Biology of Apoptosis and Necroptosis in Cancer.- 2. Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis.- 3. Micro-environmental Effects of Cell Death in Malignant Disease.- 4. Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis.- 5. Axl and Mer Receptor Tyrosine Kinases: Distinct and Non-overlapping Roles in Inflammation and Cancer?.- 6. Immunogenic Apoptotic Cell Death and Anti-cancer Immunity.- 7. Cancer Cell Death-inducing Radiotherapy – Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity.- 8. Novel Approaches to Apoptosis-inducing Therapies.- 9. Killing Is Not Enough – How Apoptosis Hijacks Tumor-associated Macrophages to Promote Cancer Progression.- Index.

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        Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy