L-Arginine in Clinical Nutrition
Samenvatting
This
text presents the application of current nutritional knowledge by physicians
and dietitians and incorporates emerging fields of science and important
discoveries. It contains seven major sections.
Section 1: Basic Processes at the Cellular Levels, Section 2: Arginine
Metabolism and Functions, Section 3: Arginine Status in Cells Related to Organ
Damage and Disease, Section 4: Arginine Status and Use in Healthy Individuals, Section
5: Arginine and Diseases of the Gastrointestinal Tract, Section 6: Therapeutic
uses of Arginine: Diabetes, Obesity and Cardiovascular Diseases and Section 7: Therapeutic Uses of Arginine: Cancer, Wound
Healing and Infectious Disease.
Written
by authors of international and national standing, leaders in the field and
trendsetters, Arginine in Clinical Nutrition is essential reading for
nutritionists and dietitians, public health scientists, doctors,
epidemiologists, health care professionals of various disciplines, policy
makers and marketing and economic strategists.
Specificaties
Inhoudsopgave
Cellular Levels.- Arginine
uptake by cells.- L-arginine and the
expression of HSP70 and p-53 proteins.- AMP-activated
protein kinase and L-arginine.- Amidine-based
compounds affecting arginine metabolism.-
Oxy- and sulfoanalogues of L-arginine.-
Regulation of expression and activity of L-arginine transporters by
nutrients and hormones: A focus in transcriptional mechanisms regulated by
glucose and insulin.- Arginine, pancreatic beta cell function and
diabetes: mechanisms of stimulated insulin release and pathways of metabolism.- Erythrocytes
by-products of arginine catabolism.- Section 2: Arginine Metabolism
and Functions.- Arginine
synthesis from enteral proline.- Arginine
and macrophages: role in classical and alternative activation.- Arginine
and TNF alpha production in macrophages: a focus on metabolism, ageing,
metabolic syndrome and type 2 diabetes.- Arginine
metabolism impairment during sepsis and diseases: causes and consequences.-
Use of arginine
with Growth Hormone Releasing Hormone (GHRH) and the endocrine response.- Serum
arginase in healthy subjects and nitric oxide.- Section 3: Arginine Status in Cells Related to Organ Damage and
Disease.- Protein Arginine Methylation of RNA-binding Proteins and Their
Impact on Human Diseases.- DNA-arginine
adducts and implications in disease.- Homoarginine
and L-arginine: Glycine amidinotransferase in stroke.- The L-arginine/asymmetric dimethylarginine (ADMA) ratio in
health and disease: an overview.- Arginine
and its transporters in colorectal cancer.-
Arginine Uptake and Its Role in the Survival of Breast Cancer Cells.- Section 4: Arginine Status and Use in
Healthy Individuals.- Arginine production during pregnancy.- L-arginine in the uterus and
placenta and during gestation in mammals.-
Oral L-arginine supplementation in young males: endocrinology, metabolic,
and physiological responses at rest and during exercise.- Metabolic
precursors of L-Arginine supplementation in sport: a focus on L-Citrulline and
L-Ornithine.- Section 5: Arginine and
Diseases of the Gastrointestinal Tract.- Arginine and its use in ameliorating Cryptosporidium parvum infection in
undernourished children.- Arginine
and Inflammatory Bowel Disease (IBD) .- Dietary L-arginine and intestinal
recovery.- Enteral and
parenteral arginine supplementation in intestinal ischemia and reperfusion
injury.- Mucosal Protection by
Arginine in the Upper Gastrointestinal Tract.- Enteral L-arginine and necrotizing enterocolitis.- Section 6: Therapeutic uses of Arginine:
Diabetes, Obesity and Cardiovascular Diseases.- L-arginine usage in Type I
diabetes: From the autoimmune event to human dietary supplementation.- Oral l-arginine supplementation and
glucose metabolism and vascular function.-
Arginine enriched apples and diabetic control.- Beneficial impact of cod protein, arginine and other
amino acids on insulin sensitivity.- Obese subjects and supplemental
L-arginine.- Mitochondrial cardiomyopathy
and usage of L-arginine.- Arginine
Measurement and Concentrations in Hypertension and other Cardiovascular Disease.- L-Arginine
and cardiovascular disease.- Arginine therapy in sickle cell
disease.- Section 7: Therapeutic Uses of Arginine: Cancer, Wound
Healing and Infectious Disease.- Role of arginine in surgical
patients with head and neck cancer.- Arginine-Incorporated
Albumin Mesospheres: A Drug Delivery System for Cancer Therapy.- Use of L-arginine and glycine
supplementation to reduce radiotherapy damage.- Arginine in Cancer Therapy.- Mechanisms of Arginine-Auxotrophic
Response and Their Cancer Therapeutic Implications.- The role of arginine in wound healing.- L-arginine and bacterial translocation: implications for health.- L-arginine in Pulmonary Tuberculosis.- Arginine
in Health and Disease: Recommended Resources and Further Reading.</p>