Aman Chandra Kaushik,
Ajay Kumar,
Shiv Bharadwaj,
Ravi Chaudhary,
Shakti Sahi
e.a.
Springer International Publishing
e druk, 2018
9783319757315
Bioinformatics Techniques for Drug Discovery
Applications for Complex Diseases
Specificaties
Paperback, blz.
|
Engels
Springer International Publishing |
e druk, 2018
ISBN13: 9783319757315
Rubricering
Onderdeel van serie
SpringerBriefs in Computer Science
Levertijd ongeveer 8 werkdagen
Samenvatting
The application of bioinformatics approaches in drug design involves an interdisciplinary array of sophisticated techniques and software tools to elucidate hidden or complex biological data. This work reviews the latest bioinformatics approaches used for drug discovery. The text covers ligand-based and structure-based approaches for computer-aided drug design, 3D pharmacophore modeling, molecular dynamics simulation, the thermodynamics of ligand−receptor and ligand−enzyme association, thermodynamic characterization and optimization, and techniques for computational genomics and proteomics.
Specificaties
ISBN13:9783319757315
Taal:Engels
Bindwijze:paperback
Uitgever:Springer International Publishing
Inhoudsopgave
<p>Brief Introduction.- Ligand-Based Approaches for Drug Design Using Computational Techniques.- Structure-Based Approaches for Drug Design Using Computational Technique.- Three-Dimensional Pharmacophore Modeling-Based Drug Design Using Computational Techniques.- Molecular Dynamics Simulation Approaches to Investigate the Dynamic Behavior of a System Through the Application of Newtonian Mechanics.- Receptor Thermodynamics of Ligand−Receptor and Ligand−Enzyme Association.- Thermodynamics Cycles and Their Application in Protein Targets.- Genomics and Proteomics Using Computational Biology.</p>