Arturo Ortega,
Arne Schousboe
Springer International Publishing
e druk, 2017
9783319557670
Glial Amino Acid Transporters
Specificaties
Gebonden, blz.
|
Engels
Springer International Publishing |
e druk, 2017
ISBN13: 9783319557670
Rubricering
Onderdeel van serie
Advances in Neurobiology
Levertijd ongeveer 8 werkdagen
Samenvatting
This ambitious compendium provides an extensive overview on the "supporting cells" of the vertebrate central nervous system, these being glial cells which far outnumber neurons but are much less understood. Covering multiple aspects of this family of transporters-- from structural properties, to their involvement in signaling and gene expression regulation, this volume presents the most recent research on the roles of glial amino acid transporters as key molecules of brain metabolism and signaling.
Specificaties
ISBN13:9783319557670
Taal:Engels
Bindwijze:gebonden
Uitgever:Springer International Publishing
Serie:Advances in Neurobiology
Inhoudsopgave
Manganese and glutamate transporters gene expression,- Glycine transportes in glia cells: structural studies.- Taurine homeostasis and volume control.- Glycine transporters and its coupling with NMDA receptors.- Revised Ion/Substrate Coupling Stoichiometry of GABA Transporters.- EAAT2 and the molecular signature of amyotrophic lateral sclerosis.- Glial GABA transporters as modulators of inhibitory signalling in epilepsy and stroke.- Glial Glutamine transporters: Beyond the glutamate/glutamine shuttle.- Glutamate transporters as signaling molecules.- Regulation of the glutamate transporters expression in glia cells.- Glutamate Transport System as a Novel Therapeutic Target in Chronic Pain: Molecular Mechanisms and Pharmacology.- Monocarboxylate transporters.- Glutamate transporters role in neurological diseases.- Astrocytic GABA-transporters:Pharmacological properties and targets for antiepileptic drugs.- Glutamate transporters in the blood-brain barrier.- Development of non-GAT1 selective inhibitors; challenges and achievements.