Silica-coated Magnetic Nanoparticles

<p>1. Introduction</p><p>1.1. Magnetic nanoparticles for biomedical applications: special emphasis as targeted drug systems.</p><p>1.2. Solid silica as platform for drug loading and transport</p><p>2. Chemical overview</p><p>2.1. Synthesis of solid silica-coated magnetic nanoparticles for drug targeting</p><p>2.2. Drug loading and release for specific diseases</p><p>2.3. Characterization techniques and drug quantification</p><p>3. Biological features</p><p>&nbsp; &nbsp; 3.1. Pharmacokinetics and biodistribution of magnetic silica nanoparticles</p><p>&nbsp; &nbsp; 3.2. Metabolism and elimination of magnetic component and silica coating</p><p>4. Toxicological insights&nbsp;</p><p>&nbsp; &nbsp; 4.1. Biocompatibility of solid silica-coated magnetic nanoparticles: an overview on specific components and on magnetic systems.&nbsp;</p><p>&nbsp; &nbsp; 4.2. In vitro and in vivo toxicology studies.</p><p>5. Overview on applications for the treatment of specific diseases</p><p>6. New insights on silica-coated magnetic nanoparticles: improving the performance of drug loading and release.</p>