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NF-κB-Related Genetic Diseases

Specificaties
Paperback, blz. | Engels
Springer International Publishing | e druk, 2016
ISBN13: 9783319258485
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Springer International Publishing e druk, 2016 9783319258485
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Samenvatting

This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.

Specificaties

ISBN13:9783319258485
Taal:Engels
Bindwijze:paperback
Uitgever:Springer International Publishing

Inhoudsopgave

1) The NF-kB signaling pathways: players and Functions.- 2) Genetic Diseases Affecting the Canonical Pathway of NF-kB Activation.- 3) Genetic Diseases Affecting hte Non-Camonical Pathway of NF-kB Activation.- 4) Genetic Diseases Affecting Ubiquitination Processes in NF-kB Signaling.- 5)Lessons Learned from Studying NF-kB Related Genetic Diseases.

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        NF-κB-Related Genetic Diseases