<p>Part 1. Overview</p><p>1. Anatomic Definitions of Borderline Resectable Pancreatic Cancer <br>Rebecca A. Snyder, Alexander A. Parikh, Kamran Idress, and Nipun B. Merchant</p><p>Part 2. Staging and Pretreatment Management</p><p>2. Imaging Evaluation of Borderline Pancreatic Cancer<br>Kyuran Ann Choe and Nicholas M. McDonald</p><p>3. Endoscopic Ultrasonography: Staging and Therapeutic Intervention<br>Girish Mishra and Rishi Pawa</p><p>4. Endoscopic and Percutaneous Biliary Drainage Procedures: Role in Preoperative Management, Diagnosis, and Palliation<br>Milton T. Smith<br> <br>Part 3. Multimodal Therapy</p><p>5. Overview of Multimodality Therapy <br>Robert de Wilton Marsh and Marshall S. Baker<br> <br>6. Role of Systemic Therapy<br>Matthew J. Reilley and Gauri Varadhachary</p><p>7. Role of Radiation Therapy<br>Neilayan Sen and Ross Abrams</p><p>8. Stereotactic Body Radiation Therapy as an Emerging Option for Localized Pancreatic Cancer <br>Rachit Kumar, Lauren M. Rosati, and Joseph M. Herman</p><p>9. Assessment of Response to Preoperative Therapy<br>André L. Mihaljevic and Jörg Kleeff</p><p>10. Emerging Systemic and Targeted Therapies<br>Trailokya Pandit and Philip A. Philip</p><p>Part 4. Surgery</p><p>11. Operative Principles in Managing Patients with Borderline Resectable Pancreas Cancer<br>Kaitlyn J. Kelly and Andrew M. Lowy</p><p>12. Is There a Role for Laparoscopic and/or Robotic Techniques for Borderline Resectable Tumors?<br>Lee M. Ocuin, Herbert J. Zeh III, and Amer H. Zureikat</p><p>13. Role and Techniques Of Vascular Resection<br>Mark J. Truty</p><p>14. Artery-First Approaches to Pancreaticoduodenectomy<br>Kyoichi Takaori and Shinji Uemoto</p><p>15. Venous Shunting Procedures for Borderline Resectable Pancreatic Cancer<br>Amir H. Fathi, Susan Tsai, Jeffrey E. Lee, Douglas B. Evans, and Kathleen K. Christians</p><p>16. The Role of the Appleby Operation and Arterial Resection in the Multimodality Management of Borderline Resectable Pancreatic Cancer <br>Ken-ichi Okada and Hiroki Yamaue</p><p>17. Surgery for Borderline Resectable Pancreatic Cancer: The Japanese Experience<br>Shuji Isaji, Masashi Kishiwada, and Hiroyuki Kato</p><p>18. The Role of Irreversible Electroporation and Other Ablative Techniques in Patients with Borderline Resectable Pancreatic Cancer <br>Robert C.G. Martin II and Rachel O’Connor</p><p>19. Surgical Approach to Borderline Resectable tumors of the Left Pancreas<br>Nicholas Spinelli and William Hawkins</p><p>20. Palliative Operations for Unresectable Pancreatic Cancer<br>Hishaam Ismael and Brian Badgwell </p>