Essentials of Clinical Research

Name: Essentials of Clinical Research
Author: Stephen P. Glasser

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Gebonden, 461 blz. | Engels

Springer International Publishing | 2e druk, 2014

ISBN13: 9783319054698

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Springer International Publishing 2e druk, 2014 9783319054698

135,19

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In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research.

All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on Comparative Effectiveness Research and Pragmatic Trials. Chapter 6 includes new material on Phase 0 Trials, expanded coverage of Futility Trials, a discussion of Medical Device approval, Off Label Drug use and the role of the FDA in regulating advertising. Additional new information includes the role of pill color and shape in association with the placebo effect and an examination of issues surrounding minority recruitment. The final chapter offers a new section on manuscript preparation along with a discussion of various guidelines being adopted by journals: CONSORT, STROBE, PRISMA, MOOSE and others; and coverage of Conflicts of Interest, Authorship, Coercive Citation, and Disclosures in Industry-Related Associations.

Building on the strengths of its predecessor in its comprehensive approach and authoritative advice, the new edition offers more of what has made this book a popular, trusted resource for students and working researchers alike.

Specificaties

ISBN13:9783319054698

Taal:Engels

Bindwijze:gebonden

Aantal pagina's:461

Uitgever:Springer International Publishing

Druk:2

Inhoudsopgave

Preface 1. The Beginning – Historical Aspects of Clinical Research, Clinical Research: Definitions, “Anatomy and Physiology,” and the Quest for “Universal Truth” Stephen P Glasser 2. Introduction to Clinical Research Concepts, Essential Characteristics of Clinical Research, Overview of Clinical Research Study Designs Stephen P Glasser 3. A Focus on Clinical Trials Stephen P Glasser 4. Alternative Interventional Study Designs Stephen P Glasser 5. Phase 4 (Postmarketing) Research Stephen P Glasser , Elizabeth Delzell, Maribel Salas 6. The Role of the USA Food and Drug Administration in Clinical Research Stephen P Glasser, Carol M. Ashton, Nelda P. Wray 7. The Placebo and Nocebo Effect Stephen P Glasser, William Frishman 8. Recruitment and Retention in Clinical Research Stephen P Glasser 9. Data Safety and Monitoring Boards (DSMBs) Stephen P Glasser MD, O. Dale Williams 10. Meta-analysis, Evidence Based Medicine, and Clinical Guidelines Stephen P Glasser, Sue Duval 11. Research Methods for Genetic Studies Sadeep Shrestha, Donna K Arnett 12. Research Methods for Pharmacoepidemiology Studies Maribel Salas, Bruno Stricker 13. Implementation Research: Beyond the Traditional Randomized Controlled Trial Amanda H. Salanitro, Lauren Powell, Carlos A. Estrada14. Research Methodology for Studies of Diagnostic Tests Stephen P Glasser 15. Statistical Power & Sample Size: Some Fundamentals For Clinician Researchers J. Michael Oakes 16. Association, Cause, and Correlation Stephen P Glasser, Gary Cutter 17. Bias, Confounding, and Effect Modification (Interaction) Stephen P Glasser 18. It’s All About Uncertainty Stephen P Glasser, George Howard 19. Grant and Manuscript Writing Donna K Arnett 20. The Media and Clinical Research Stephen P Glasser MD 21. Mentoring and the Mentee Stephen P Glasser, Edward W Hook III 22. Presentation Skills: How to Present Research Results Stephen P Glasser

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