Annual Update in Intensive Care and Emergency Medicine 2023

<p><p>Part I. Precision Medicine.- The role of transcriptomics in redefining critical illness.- Metagenomic sequencing in the ICU for precision diagnosis of critical infectious illnesses.- Risk stratification and precision medicine: is it feasible for severe infections?.- Interrogating the sepsis host immune response using cytomics.- Precision medicine in septic shock.- Part II. Sepsis Biomarkers And Organ Dysfunction Scores.- Host response biomarkers for sepsis In the emergency room.- Repetitive assessment of biomarker combinations as a new paradigm to detect sepsis early.- Organ dysfunction scores in the adult ICU.- Part III. ARDS.- Ex vivo lung perfusion models to explore the pathobiology of ARDS.- Interpretation of lung perfusion in ARDS.- A structured diagnostic algorithm for patients with ARDS.- Hemodynamic implications of prone positioning in patients with ARDS.- Part IV. Ventilatory Support.- Update on the management of acute respiratory failure using non-invasive ventilation and pulse oximetry.- Managing the physiologically difficult airway in critically ill adults.- Dyspnea in patients receiving invasivemechanical ventilation.- The potential risks of pressure support ventilation.- Advancing sedation strategies to improve clinical outcomes in ventilated critically ill patients.- Part V. Extracorporeal Support Setting and monitoring of mechanical ventilation during venovenous ECMO.- Early mobilization of patients receiving ECMO for respiratory failure.- Physiological adaptations during weaning from venovenous ECMO.-Novel strategies to enhance the efficiency of extracorporeal CO2.- Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: a systematic approach.- Temporary and durable mechanical circulatory support in the ICU.- Part VI. Fluids and Transfusion.- Venous congestion: why examine the abdomen with ultrasound in critically ill patients?.- The most important questions in the current practice of transfusion of critically bleeding patients.- Part VII. Acute Renal Failure.- Fluid management and acute kidney injury.- Cardiorenal syndrome 1: what’s in a name?.- Part VIII. The Microcirculation and Metabolism.- Update on the microcirculatoryassessment of the critically ill patient.- Intracellular measurements of micronutrients in critically ill patients.- Optimal glycemic targets in critically ill patients with diabetes.- Part IX: A Look Back at COVID-19.- Hydroxychloroquine: time for reappraisal of its effect in COVID-19 patients.- Blood purification in COVID-19 outside acute kidney injury.- Part X. Neurologic Considerations.- Epidemiology, outcomes and costs of pediatric traumatic brain injury patients treated in the ICU.- Quality improvements in the determination of death by neurologic criteria around the world.- Part XI. Obstetric Issues.- COVID-19-induced ARDS in pregnancy: implications for the non-COVID era.- Amniotic fluid embolism.- Part XII. Pre and Post-Intensive Care.- Remote telehealth aid during humanitarian crisis.- Boarding in the emergency department: challenges and success strategies to mitigate the current crisis.- Post-intensive care syndrome revisited in light of the COVID-19 pandemic.- Part XIII. Ethical Issues.-Rethinking the role of palliative care in the ICU.</p></p>