Review of the Pathophysiology of the Alloimmune response.- A Comprehensive Review of Calcineurin Inhibitors Used for Immunosuppression in Cardiac Transplantation.- Anti-proliferative Agents.- Mechanistic Target of Rapamycin (mTOR) Inhibitors.- Corticosteroids.- Induction therapy and antibodies.- Immunosuppression and Heart Transplantation.- Immunosuppression and Lung Transplantation.- Immunosuppression and renal transplant recipients.- Immunosuppression in Rheumatologic and Auto-immune Disease.- Immunosuppression in Bone Marrow Transplantation.- Immunosuppression in Multiple Sclerosis and Other Neurologic Disorders.- Novel immunosuppressive agents for the treatment of organ transplants.- Adverse Effects of Immunosuppression: Infections.- Malignancy: An Adverse Effect of Immunosuppression.- Adverse Effects of Immunosuppression:Nephrotoxicity, Hypertension and Metabolic Disease.