Sourcebook of Models for Biomedical Research
Samenvatting
The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.
Specificaties
Inhoudsopgave
P. Michael Conn, PhD
connm@ohsu.edu
ONPRC/OHSU
INTRODUCTORY
1
Animal models for human diseases: an overview
Jann Hau
JHAU@emed.ku.dk
Panum Instituttet
2
Selection of biomedical animal models
Michael S. Rand, DVM, DACLAM
mrand@email.arizona.edu
University of Arizona
3
Improved models for animal research
Ernesto Bockamp, Dr.rer.nat. Leonid Eshkind, PhD Jan Hengstler, MD Rolf Sprengel, Dr. rer.nat.
bockamp@mail.uni-mainz.de
Johannes Gutenberg-Universität Mainz
GENERAL CONSIDERATIONS
4
The ethical basis for animal use in research
James V. Parker, PhD
culligank@comcast.net
5
Bibliographic searching tools on disease models to locate alternatives for animals in research: A website companion
Lynette A. Hart Mary W. Wood
lahart@ucdavis.edu
University of California - Davis
6
NIH policies on sharing of model organisms and related research resources
Norka Ruiz Bravo, PhD Charlene Cho, PhD JP Kim, JD, MBA, MSc, MALS
ruizbran@od.nih.gov
NIH
7
Databases for biomedical animal resources
Richard L. Crawford, DVM Tim Allen, MS
AWKC@val.usda.gov
UDSA
8
Psychological enrichment for animals in captivity
Kristine Coleman
colemank@ohsu.edu
ONPRC/OHSU
WELL-ESTABLISHED MODELS
Yeast, Worms, Flies, Sea Animals and Birds
9
Integrated network modeling of molecular and genetic interactions
Gregory W Carter, PhD Vesteinn Thorsson, PhD Timothy Galitski,PhD
gcarter@systemsbiology.net
Institute for Systems Biology
10
The sponge as a model of cellular recognition
Xavier Fernandez-Busquets, PhD
xfernandez_busquets@ub.edu
University of Barcelona
11
Sea urchin embryo — a model system for analyzing a variety of cellular activities during early development
Tetsuya Kominami Hiromi Takata
tkom@sci.ehime-u.ac.jp
Ehime University
12
C. elegans models of human neurodegenerative deseases: a powerful tool to identify molecular mechanisms and novel therapeutic targets
Richard Nass, PhD Lihsia Chen
richard.nass@vanderbilt.edu
Vanderbilt University Medical Center
13
Zebrafish as a model for development
Brian A Link, PhD Sean G. Megason, PhD
blink@mail.mcw.edu
Medical College of Wisconsin
14
Zebrafish as a model for studying adult effects of challenges to the embryonic nervous system
Elwood A. Linney, PhD Nicole Marie Roy, PhD
elwood.linney@duke.edu
Duke University Medical Center
15
Modeling cognitive and neurodegenerative disorders in Drosophila melanogaster
Minoru Saitoe Junjiro Horiuchi
saitoe@tmin.ac.jp
Tokyo Metropolitan Institute for Neuroscience (TMIN)
16
Biomedical research with honey bees
Michelle M. Elekonich, PhD
michelle.elekonich@unlv.edu
University of Nevada Las Vegas
17
Establishing and maintaining a Xenopus laevis colony for research laboratories
Michael Levin, PhD Punita Koustubhan Debra Sorocco
mlevin@forsyth.org
The Forsyth Center for Regenerative and Developmental Biology and Harvard School of Dental Medicine
18
The chicken as a model organism
Janice M. Bahr,