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Clinical Trial Optimization Using R

Specificaties
Gebonden, 338 blz. | Engels
CRC Press | 1e druk, 2017
ISBN13: 9781498735070
Rubricering
CRC Press 1e druk, 2017 9781498735070
Verwachte levertijd ongeveer 11 werkdagen

Samenvatting

Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies. It provides the clinical researcher with a powerful evaluation paradigm, as well as supportive R tools, to evaluate and select among simultaneous competing designs or analysis options. It is applicable broadly to statisticians and other quantitative clinical trialists, who have an interest in optimizing clinical trials, clinical trial programs, or associated analytics and decision making.

This book presents in depth the Clinical Scenario Evaluation (CSE) framework, and discusses optimization strategies, including the quantitative assessment of tradeoffs. A variety of common development challenges are evaluated as case studies, and used to show how this framework both simplifies and optimizes strategy selection. Specific settings include optimizing adaptive designs, multiplicity and subgroup analysis strategies, and overall development decision-making criteria around Go/No-Go. After this book, the reader will be equipped to extend the CSE framework to their particular development challenges as well.

Specificaties

ISBN13:9781498735070
Taal:Engels
Bindwijze:Gebonden
Aantal pagina's:338
Uitgever:CRC Press
Druk:1

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        Clinical Trial Optimization Using R