The Multiple Therapeutic Targets of A20

Specificaties
Paperback, blz. | Engels
Springer New York | e druk, 2016
ISBN13: 9781493949656
Rubricering
Springer New York e druk, 2016 9781493949656
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Samenvatting

This book is meant to provide the most current knowledge regarding the mechanisms of action of A20, if its versatile functions and their validation in animal models of human disease and its promise as a diagnostic biomarker and therapeutic target.

Specificaties

ISBN13:9781493949656
Taal:Engels
Bindwijze:paperback
Uitgever:Springer New York

Inhoudsopgave

A20—A Bipartite Ubiquitin Editing Enzyme with Immunoregulatory Potential.- The Biology of A20-Binding Inhibitors of NF- κB Activation (Abins).- The Biology of A20-Like Molecules.- Anti-Viral Tetris: Modulation of the Innate Anti-Viral Immune Response by A20.- A20 Expressing Tumors and Anticancer Drug Resistance.- Translational Studies of A20 in Atherosclerosis and Cardiovascular Disease.- A Biomarker of Allograft Outcome: A Showcase in Kidney Transplantation.- A20—An Omnipotent Protein in the Liver: Prometheus Myth Resolved?.- Emerging Roles for A20 in Islet Biology and Pathology.- Single Nucleotide Polymorphisms at the TNFAIP3/A20 Locus and Susceptibility/Resistance to Inflammatory and Autoimmune Diseases.

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        The Multiple Therapeutic Targets of A20