Aging and Heart Failure

Mechanisms and Management

Specificaties
Paperback, blz. | Engels
Springer New York | e druk, 2016
ISBN13: 9781493944231
Rubricering
Springer New York e druk, 2016 9781493944231
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This book synthesizes the major research advances in molecular, biochemical and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists and internists.

Specificaties

ISBN13:9781493944231
Taal:Engels
Bindwijze:paperback
Uitgever:Springer New York

Inhoudsopgave

<p>Ch. 1: Changing demographics of the aging population with heart failure and implications for therapy</p><p>            Bodh I. Jugdutt</p><p>Ch. 2: Biology of aging and implications for heart failure therapy and prevention</p><p>            Bodh I. Jugdutt</p><p>Ch. 3: Hypertension and prevention of diastolic heart failure in the aging population</p><p>            Wilbert S. Aronow</p><p>Maciej Banach</p><p>Ali Ahmed</p><p>Ch. 4: Aging and optimal therapy of systolic heart failure in the elderly</p><p>            Nakul Chander Sharma</p><p>Bodh I. Jugdutt</p><p> </p><p>Ch. 5: Atrial fibrillation and heart failure in the aging population</p><p>            Pedram Kazemian</p><p>Bodh I. Jugdutt</p><p>Ch. 6: Optimizing therapy of heart failure in the aging population with monitoring in clinics</p><p>            John R. Dimitry</p><p>Justin A. Ezekowitz</p><p>Ch. 7:  Cardiac alterations in aging, hypertension and diastolic heart failure</p><p>            Edith Pituskin</p><p>D. Ian Paterson</p><p>Ch. 8: Polypharmacy and adverse drug reactions in the aging population with heart failure</p><p>            Michael W. Rich</p><p>William J. Nienaber</p><p>Ch. 9: Aging-related changes in vascular biology and implications for heart failure therapy in the aging population</p><p>            Michael Sean McMurtry</p><p>Ch. 10: Biomarkers and optimal management of heart failure in the aging population</p><p>            Hanna K. Gaggin </p><p>James L. Januzzi, Jr.</p><p>Ch. 11: Benefits of Exercise in the elderly</p><p>            Ezra A. Amsterdam</p><p>C. Tissa Kappagoda</p><p>Ch. 12: The RAAS in heart failure: an update on clinical trials and opportunities for therapy</p><p>            C. Tissa Kappagoda</p><p>Ezra A. Amsterdam</p><p>Ch. 13: Aging and diastolic dysfunction – the interplay of inflammation and extracellular matrix regulation         </p><p>            Peter Moritz Becher</p><p>Dirk Westermann,</p><p>Carsten Tschöpe</p><p>Ch. 14: Reperfusion and vasodilator therapy in elderly patients with STEMI and heart failure. Improving outcomes</p><p>Bodh I. Jugdutt, </p><p>Anwar Jelani</p><p>Seraj Abualnaja</p><p>Nakul Chander Sharma</p><p>Joseph Szeman Wong</p><p>Ch. 15: Erythropoietin therapy for heart failure</p><p>            Margarita Borovka</p><p>Mathew S. Maurer</p><p>Ch. 16: Role of resistin in heart failure in the elderly</p><p>            Yasuchika Takeishi</p><p>Ch. 17: Role of coronary artery calcium in cardiovascular risk stratification and management in the aging population</p><p>            Craig R. Butler</p><p>Paolo Raggi</p><p>Ch. 18: Aging-and remodeling of the RAS and RAAS and related pathways. Implications for heart failure therapy</p><p>Bodh I. Jugdutt</p><p>Ch. 19: Aging and right ventricular failure from pulmonary hypertension: Effect of right ventricular and pulmonary artery remodeling</p><p>Joseph Szeman Wong</p><p>Bodh I. Jugdutt</p><p>Ch. 20: Biomarkers of cardiovascular aging</p><p>           Nirankar S. Neki</p><p>Paramjit S. Tappia</p><p>Naranjan S. Dhalla</p><p>Ch. 21: Changes in the heart that accompany advancing age: Humans to molecules</p><p>            Edward G. Lakatta</p><p>Harold A. Spurgeon</p><p>Andzej M. Janczewski</p><p>Ch. 22: Aging-related changes in cell death and cell survival pathways and implications for heart failure therapy</p><p>            Guido R.Y. De Meyer</p><p>Dorien M. Schrijvers</p><p>Wim Martinet</p><p>Ch. 23: Aging-related changes in telomeres and telomerases and implications for heart failure therapy</p><p>            Pim van der Harst</p><p>Dirk J. van Veldhuisen</p><p>Ch. 24: Aging associated alterations in myocardial inflammation and fibrosis: pathophysiological perspectives and clinical implications</p><p>            Arti V. Shinde</p><p>Nikolaos G Frangogiannis</p><p>Ch. 25: Aging-related changes in extracellular matrix: implications for ventricular remodeling following myocardial infarction  </p><p>            Nguyen T. Nguyen</p><p>Andriy Yabluchanskiy</p><p>Lisandra E. de Castro Brás</p><p>Yu-Fang Jin</p><p>Merry L. Lindsey</p><p>Ch. 26: Calcium handling defects and changes in cardiac function in the aging heart</p><p>            Adriana Adameova</p><p>Nirankar S. Neki</p><p>Paramjit S. Tappia</p><p>Naranjan S. Dhalla</p><p>Ch. 27: Integrins: Implications for aging in heart failure therapy</p><p>            Laura L. Daniel</p><p>William L. Joyner</p><p>Mahipal Singh</p><p>Krishna Singh</p><p>Ch. 28: Adipokines as novel biomarkers in aging and heart failure</p><p>            Ken Shinmura</p><p>Ch. 29: Aging-related changes in cellular and molecular mechanisms of post-infarction remodeling. Implications for heart failure therapy</p><p>            Henry Han-Jen Shih</p><p>Andrew J. Boyle</p><p>Ch. 30: Aging-related changes in mitochondrial function and implication for heart failure therapy</p><p>            Satoaki Matoba</p><p>Atsushi Hoshino</p><p>Hiroaki Matsubara</p><p>Ch. 31: Regulation of SERCA via oxidative modifications: Implications for the pathophysiology of diastolic dysfunction in the aging heart</p><p>            Fuzhong Qin</p><p>Richard A. Cohen</p><p>Wilson S. Colucci</p><p>Ch. 32: SMP-30 and aging-related cardiac remodeling and heart failure</p><p>            Satoshi Suzuki</p>Yasuchika Takeishi

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        Aging and Heart Failure