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Lipoproteins in Diabetes Mellitus

Specificaties
Paperback, blz. | Engels
Springer New York | e druk, 2015
ISBN13: 9781493932184
Rubricering
Springer New York e druk, 2015 9781493932184
Onderdeel van serie Contemporary Diabetes
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed.

An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes.

Specificaties

ISBN13:9781493932184
Taal:Engels
Bindwijze:paperback
Uitgever:Springer New York

Inhoudsopgave

<p>Ch1: Laboratory Assessment of Lipoproteins in Diabetes</p><p>David R. Sullivan</p><p>Barry Lewis</p><p> </p><p>Ch2: Lipoprotein Subclasses and Cardiovascular Disease Risk in Insulin Resistance Diabetes</p><p>Michael Cobble</p><p>Patrick D. Mize</p><p>Eliot A. Brinton</p><p> </p><p>Ch3: Insulin Resistance and Atherosclerosis</p><p>Kamalpreet Singh</p><p>Vasudevan A. Raghavan</p><p> </p><p>Ch4: Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes</p><p>Thomas D. Dayspring</p><p> </p><p>Ch5: Lipoprotein Metabolism and Alterations induced by insulin resistance and diabetes</p><p>Gerald H. Tomkin</p><p>Daphne Owens </p><p> </p><p>Ch6: Production and Metabolism of Triglyceride-Rich Lipoproteins in both the Normal and Diabetic States                                                                                                                                                                       </p><p>Angela Pirillo</p><p>Giuseppe D. Norata</p><p>Alberico L. Catapano</p><p> </p><p>Ch7: Lipoprotein(a): Structure, Metabolism and Pathophysiology</p><p>Alicia J. Jenkins</p><p>Karam M. Kostner</p><p>Gerhard M. Kostner</p><p> </p><p>Ch8: Lipoprotein Glycation in Diabetes Mellitus</p><p>Alicia J. Jenkins</p><p>Richard L. Klein</p><p>Andrzej S. Januszewski</p><p></p><p><br/>Ch9: Lipoprotein (LDL and  HDL) Oxidation in Diabetes Mellitus</p><p>Marielle Kaplan</p><p>Michael Aviram</p><p>Tony Hayek</p><p> </p><p>Ch10: The Role of Modified Forms of LDL and Corresponding Autoantibodies in the Development of Complications in Diabetes</p><p>Maria F. Lopes-Virella</p><p>Gabriel Virella</p><p> </p><p>Ch11: Lipid – Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes</p><p>Narin Osman</p><p>Peter J.</p> Little<p></p><p> </p><p>Ch12: Tools for Assessing Lipoprotein Metabolism in Diabetes Mellitus</p><p>Richard L. Klein</p><p> </p><p>Ch13: Endothelial Dysfunction and Dyslipidaemia in Type 2 Diabetes: Pathogenesis, Significance and Therapy</p><p>Sandra J. Hamilton</p><p>Gerald F. Watts</p><p> </p><p>Ch14: Lipoproteins and Diabetic Nephropathy</p><p>Ville-Petteri Mäkinen</p><p>Nina Tolonen</p><p>Per-Henrik Groop</p><p> </p><p>Ch15: Roles of Extravasated and Modified Plasma Lipoproteins in Diabetic Retinopathy</p><p>Mingyuan Wu</p><p>Timothy J. Lyons</p><p> </p><p>Ch16: Effects of Lifestyle (Diet, Plant Sterols, Excercise) and Glycemic Control on Lipoporteins in Diabetes    </p><p>Peter Clifton</p><p> </p><p>Ch17: About Randomised Clinical Trials Related to Lipoproteins in Diabetes Mellitus</p><p>Anthony Keech</p><p>Alicia J. Jenkins</p><p>Val Gebski</p><p> </p><p>Ch18: Statin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients</p><p>Seth S. Martin</p><p>Parag H. Joshi</p><p>Steven R. Jones</p><p> </p><p>Ch19: The PPAR System in Diabetes</p><p>Jean Claude Ansquer</p><p>Christelle Foucher</p><p> </p><p>Ch20: Fibrate Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients</p><p>Eliot A. Brinton</p><p> </p><p>Ch21: Niacin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients</p><p>Henry A. Tran</p><p>Arthur Z. Schwartzbard</p><p>James A. Underberg</p><p> </p><p>Ch22: Cholesterol Absorption Inhibitors (Ezetimibe) and Bile Acid Binding Resins (Colesevelam HCl) as Therapy for Dyslipidemia in Patients with Diabetes Mellitus</p><p>Harold Bays</p><p> </p><p>Ch23: Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes                                 </p><p>Peter J. Little</p><p>Alan Chait</p><p>Andrzej S. Januszewski</p><p>Alex Bobik</p><p>David O’Neal</p><p>Alicia J. Jenkins</p>

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        Lipoproteins in Diabetes Mellitus