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The New Angiotherapy

Specificaties
Paperback, 610 blz. | Engels
Humana Press | 0e druk, 2013
ISBN13: 9781468496574
Rubricering
Humana Press 0e druk, 2013 9781468496574
€ 183,99
Levertijd ongeveer 8 werkdagen

Samenvatting

An international team of experts critically review the recent progress in basic and applied research in angiogenesis. Their cutting-edge discussion ranges from the stimulation and repression of angiogenesis to the discovery of novel targets and the use angiotherapy in the clinic. They also detail the fundamental concepts in the physiology and pathophysiology of angiogenesis and evaluate the potential of angiotherapy in the management of angiogenic disease, highlighting some of the angiogenics and antiangiogenics both in development and in clinical trials.

Specificaties

ISBN13:9781468496574
Taal:Engels
Bindwijze:paperback
Aantal pagina's:610
Uitgever:Humana Press
Druk:0

Inhoudsopgave

I. Concepts

Vasculogenesis and Angiogenesis
Robert Auerbach and Wanda Auerbach

Angiogenesis-Regulating Cytokines
Michael S. Pepper, Stefano J. Mandriota, and Roberto Montesano

The Angiopoietins
Pamela F. Jones

Regulation of Vascular Morphogenesis by Extracellular Matrix Proteins
Amy D. Bradshaw and E. Helene Sage

II. Angiogenesis in Health and Disease

Integrin Receptors and the Regulation of Angiogenesis
Dorothy Rodriguez and Peter C. Brooks

Vasoactive Peptides in Angiogenesis
David Andrew Walsh and Tai-Ping D. Fan

Angiogenesis in Wound Healing and Surgery
Wayne A. Morrison, Geraldine M. Mitchell, Jane E. Barker, Tamara Konopka, and Alastair G. Stewart

Angiogenesis and Vascular Endothelial Growth Factor (VEGF) in Reproduction
D. Stephen Charnock-Jones, Yulong He, and Stephen K. Smith

Rheumatoid Arthritis: A Target for Anti-Angiogenic Therapy?
Ewa M. Paleolog and Jadwiga M. Miotla

Diagnostic and Prognostic Significance of Tumor Angiogenesis
Stephen B. Fox and Adrian L. Harris

III. Stimulation of Angiogenesis [Therapeutic Angiogenesis]

Hyaluronan Oligosaccharides Promote Wound Repair: Its Size-Dependent Regulation of Angiogenesis
David C. West and Tai-Ping D. Fan

Role of Thymic Peptides in Wound Healing
Hynda K. Kleinman, Derrick S. Grant, and Katherine M. Malinda

Angiogenesis and Growth Factors in Ulcer Healing
Sandor Szabo, Yuen Shing, M. Judah Folkman, Aron Vincze, Zoltan Gombos, Xiaoming Deng, Tetayana Khomenko, and Masashi Yoshida

Angiogenesis in Skeletal and Cardiac Muscle: Role of Mechanical Factors
Margaret D. Brown and Olga Hudlická

Therapeutic Angiogenesis for the Treatment of Cardiovascular Disease
Jeffrey M. Isner and Takayuki Asahara

Therapeutic Angiogenesis for the Heart
JohannesWaltenberger and Vinzenz Hombach

Contact-Guided Angiogenesis and Tissue Engineering
Robert A. Brown, Giorgio Terenghi, and Clive D. McFarland

IV. Anti-Angiogenesis

Inhibitors of Matrix Metalloproteinases
Peter D. Brown and William G. Stetler-Stevenson

Control of Angiogenesis by Microbial Products
Tsutomu Oikawa

Interaction of Angiogenic Growth Factors with Endothelial Cell Heparan Sulfate Proteoglycans: Implication for the Development of Angiostatic Compounds
Marco Rusnati, Giovanni Tulipano, and Marco Presta

2-Methoxyestradiol: A Novel Endogenous Chemotherapeutic and Anti-Angiogenic Agent
Victor S. Pribluda, Theresa M. LaVallee, and Shawn J. Green

V. Novel Targets

Receptor Tyrosine Kinases in Angiogenesis
Laura K. Shawver, Kenneth E. Lipson, T. Annie T. Fong, Gerald McMahon, and Laurie M. Strawn

Targeting Gene Therapy to the Tumor Vasculature
Kelvin K. W. Lau and Roy Bicknell

Antibody Targeting of Tumor Vasculature
J. Wilson, David C. West and Philip E. Thorpe

Endothelial Monocyte-Activating Polypeptide II: A Novel Injury Signal?
Cliff Murray and Maarten Tas

CD105 Antibody for Targeting of Tumor Vascular Endothelial Cells
Ben K. Seon and Shant Kumar

VI. Angiotherapy in the Clinic

Design of Pharmacological and Diagnostic Strategies for Angiogenesis-Dependent Diseases
Lucia Morbidelli and Marina Ziche

Design of Clinical Trials for Anti-Angiogenics
Elise C. Kohn

Angiogeneis Therapies: Concepts, Clinical Trials, and Considerations for New Drug Development
William W. Li, Vincent W. Li, and Dimitris Tsakayannis

Angiostatin and Endostatin: Recent Advances in Their Biology, Pharmacokinetics, and Potential Clinical Applications
Jesus V. Soriano and B. Kim Lee Sim
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        The New Angiotherapy