In Vivo Immunology

Session 1 Bone Marrow, B Cell Differentiation, and the B Cell System.- Chairman’s Introduction: Bone Marrow and B Cell Differentiation.- Migration of Erythropoietic and Prebursal Stem Cells from the Early Chicken Embryo to the Yolk Sac.- Antigens Associated with Bursal and Thymic Reticular Epithelial Cells.- The Development of B Lymphocytes and Their Reactivity in Pig Fetuses.- Regulation of B Cell Development in Mouse Bone Marrow.- Distribution and Functional Properties of PNA+ and PNA- Cells in Central and Peripheral Lymphoid Organs of the Chicken.- Peanut Agglutinin (PNA) Binding as a Marker for Immature Human B Lymphocytes. Is Bone Marrow Not the Complete Bursa-Equivalent?.- Functional Studies on Subpopulations of B-Lymphocytes and Bone Marrow Cells.- Human Sessile B Lymphocyte Marker Defined by a Monoclonal Antibody.- Marginal Zones: The Largest B Cell Compartment of the Rat Spleen.- The Proliferative Activity of Antibody Forming Cells in the Mouse Bone Marrow.- The Origin of Marginal-Zone Cells.- Functional Antigen Binding by the Defective B Cells of CBA/N Mice.- The Role of Bursal Microenvironment in the Maturation of B Cells.- Fluorescence Activated Cell Sorter Analysis of Murine B Cell Development.- Pre B Cell Leukaemia in the Rat.- Differences in In Vivo Functional Capacities of Avian Precursor B and T Cells Following In Vitro Incubation.- Lymphoid Antigens on Non-lymphoid Factor-Dependent Haemopoietic Cell Lines.- Session 2 Lymphocyte Migration.- Chairman’s Introduction: Experimental Approaches to Lymphocyte Traffic: Pitfalls of the Tracer Sample Method.- Two Populations of Murine LPS-Responsive B Lymphocytes Differing in Recirculatory Capacity.- A Method for Studying the Dynamics of the Primary Migration of Human Lymphocytes Using Indium-III Oxine Cell Labelling.- LYT Phenotype and Lectin Binding Properties of Mouse Lymphocytes Which Enter Lymph Nodes.- Unilateral Localization of Hapten-Specific B Memory Cells in Lymph Node Draining A Footpad Injection of Antigen.- Organ-Specific Homing of B Cell Hybridomas.- Isolation of Factors Causing Enhanced Lymphocyte Adherence to High Endothelial Venules In Vitro.- Lymphocyte-Endothelial Interactions and Histocompatibility Restriction.- Selective Migration of Murine Lymphocytes and Lymphoblast Populations and the Role of Endothelial Cell Recognition.- The Effect of Stimulated Macrophages on High Endothelial Venules and Germinal Centres in Lymph Nodes of Rat.- Homing Pattern of Newly Formed Splenic Lymphocytes.- The Efficiency of Entry of Lymphoid Cells into Lymphoid and Non-lymphoid Tissues.- Morphological Aspects of the Local Immune Response to Influenza in Rats.- Session 3 Thymus, T Cell Differentiation, and the T Cell System.- Chairman’s Introduction: Thymus, T Cell Differentiation and the T Cell System.- Detection of MHC, THY-1, LYT-1 and LYT-2 Antigens in the Developing Mouse Thymus.- Role of Thymic Medullary Lymphocytes in the Intra-Thymic Maturation Process.- Sequential Development of THY-1+ Subpopulations in Regenerating Thymus After Bone Marrow Transplantation.- “Thymic Nurse Cells” Contain the First Virus Producing Cells After Inoculation of the Radiation Leukemia Virus in C57BL/Ka Mice.- Studies on the Maturity of Cells Migrating From the Thymus to the Periphery in Mice.- Lymphocytes in Mice with Membrane Antigens Common to Human Thymocytes.- Cloned T Cell Progenitors From Mouse Bone Marrow Give Rise to Lymphocytes with Multiple Anti-H-2 Reactivities.- Frequency and Restriction of Cytotoxic T Lymphocyte Precursors in Neonatally Thymectomized Mice.- Accumulation of Mature T and B Cells and Abnormalities of Lymphocyte Traffic in the Thymus of Aged NZB × SJL F1 Female Mice.- Structural and Functional Alterations of the Aging Human Thymus.- Study of Beta Adrenoceptors on Subpopulations of Thymocytes Separated on Ficoll-Hypaque Density Gradients.- Lymphocyte Differentiation in the Rabbit Thymus.- Monoclonal Antibodies Against Rat T Cells.- Ontogeny of the Immune System in Fish — Role of the Thymus.- The Thymus-Hypophysis Interaction in the Developing Chick Embryo: Thymic Epithelial Cells in Hypophysectomized Embryos.- Monoclonal Antibodies to Cell Surface Antigens on Lymphoid and Non-lymphoid Cells of the Mouse.- Cultured Thymic Epithelium. Its Morphological Characterization and Biological Effect In Vivo in Athymic Nude Rats.- Ontogeny of LYT 1 and LYT 123 Lymphocytes in the Mouse Thymus.- Session 4 Non-Lymphoid Cells: Factors in Immune Reactions.- Chairman’s Introduction: Non-lymphoid Cells and Factors in Immune Reactions.- Evidence for Extrinsic Origin of Ia Positive Cells in Embryonic Murine Thymus.- Ia Positive Cells in the Medulla of Rat Thymus Are Bone Marrow Derived.- Morphological Assessment of Immunologically Relevant Cells in the Thymus.- The Principal Cells in the Thymus Expressing MHC Antigens Are Epithelial.- Interdigitating Cells. A Guiding Cell Line in T-Cell Reactivity.- The Immunological Significance of Birbeck Granule Containing Cells.- A Comparative Study of Accessory Cells Derived from the Peritoneum and from Solid Tissues.- Characterization of Bone Marrow Derived Macrophage as Ia-Bearing Accessory Cells.- The Frequency and Surface Markers of Antigen-Laden Cells in Thoracic Duct Lymph.- Rat Thymus Micro-Environment: An Ultrastructural and Functional Characterization.- The Effect of Veiled Cells on Lymphocyte Function.- Effect of an Acute Viral Infection by a Silent Virus on the Humoral Immune Responses.- Modulatory Effects of Splenic Accessory Cells on In Vivo Antibody Response.- Macrophages, Langerhans Cells, Interdigitating and Dendritic Accessory Cells: A Summary.- Session 5 Lymphoepithelial Relations: GALT/BALT.- Chairman’s Introduction: Gut and Bronchus Associated Lymphoid Tissue: An Overview.- Intestinal Mast Cells and Their Relation to Mesenteric Lymph Nodes.- Ultrastructural Analysis of Lymphoid Subpopulations and Their Relation to Stationary Cells in the Epithelial Crypts and the Follicles During Early Ontogeny of the Human Tonsilla Palatina.- Histology and Immunohistochemistry of Bronchus Associated Lymphoid Tissue (BALT) in the Rat.- Preferential Uptake of Soluble Antigen by Respiratory Tract Epithelium Overlying Bronchus-Associated Lymphoid Tissue in the Rat.- Macrophage Function in Peyer’s Patch Epithelium.- Development of Immune Potential and Migration Pattern of Cells from Germfree (GF) and Conventionally (CONV) Reared Rats.- Unique Functional Characteristics of Mucosal Mast Cells.- Session 6 Basic Immunological Aspects of GVHR.- Chairman’s Introduction: H-2-Restriction of T Cells Mediating Lethal Graft-Versus-Host-Disease to Minor Histocompatibility Determinants.- Induction of Either Acute or Chronic Graft-Versus-Host-Disease Due to Genetic Differences Among Donor T Cells.- Subpopulations of T Cells in the Rat That Mediate Graft-Versus-Host Reactions and Lethal Graft-Versus-Host Disease.- Alterated Immunological Reactivity in Rats Sustaining a Graft-Versus-Host-Reaction (GvHR).- Specific Systemic Graft-Versus-Host Resistance: Failure to Induce in Adult F1 Rats Tolerized at Birth to Anti-MHC Receptors on Parental T Cells.- The Rowett Nude (rnu) Rat as a Host in the Popliteal Lymph Node GVH Reaction.- Specific Suppression of Anti-Host Immune Reactivity in Graft-Versus-Host Reaction.- Systemic Immunomodulation Induced by a “Loco-Regional” GVHR in the Rat.- Lymphoid Tissue Transplantation in Rats Leads to a GVHR, Inducing a Specific T-Cell Mediated Autoreactivity Against MHC-Antigens.- Session 7 Immune Response Regulation.- Immunoregulatory Factors Produced by Activated Lymph Nodes In Vivo.- Impairment of Antigen-Specific T Cell Proliferative Response in B Cell Suppressed Mice.- T Cell-Dependent B Cell Lymphoproliferation and Activation Induced by the Drug Diphenylhydantoin.- Negative Selection of Discrete Subgroups of T Helper Cells Restricted by Determinants Present on I-A and I-A/E Molecules.- Induction and Suppression of Delayed-Type Hypersensitivity to Sheep Red Blood Cells by Anti-Idiotypic Antiserum.- Genes of the Major Histocompatibility Complex Control Transmission of Information Between Initiator and Recruited T Lymphocyte.- The Role of I-J Subregion Gene Products in the Inhibition of Delayed-Type Hypersensitivity to Major Histocompatibility Antigens by Specific Suppressor T Cells.- Nonspecific Suppression of Anti-Graft Immunity by Antigen-Specific T Suppressor Cells.- Cell-Interactions in the Splenic Suppression Caused by Antigen-Feeding.- Autoimmune Disease Strongly Resembling Systemic Lupus Erythematosus (SLE) in F1 Mice Undergoing Graft-Versus-Host Reaction (GVHR).- Impaired Host Resistance Against Local JMV Marek’s Disease Tumors After Thymectomy and After Bursectomy.- Lack of Suppressor T Cells in Renal Transplant Recipients and Activation by Aminophylline.- Secondary In Vivo Cytotoxic T Cell Responses To Minor Histocompatibility Antigens.- Cellular and Genetic Basis of the Relative Resistance to the Induction of Experimental Allergic Encephalomelitis (EAE) in Albino Oxford (AO) Rats.- Quantitative Aspects of the Nonspecific Humoral Immune Response to Sheep Erythrocytes.- The Effect of Cyclosporin A On Spontaneous Autoimmune Thyroiditis in Obese Strain (OS) Chickens.- Characteristics of IL-3 Derived and IL-3 Dependent Lymphocyte Cell Lines.- Developmental Aspects of T-Suppressor Cells Induced by Hapten-Carrier Conjugates.- Immune Response Regulation.- Session 8 The Still Unsolved Mystery of the Germinal Center (Continued).- Chairman’s Introduction.- The Role of T Cells in B Cell Priming and Germinal Centre Development.- Expression of T Cell Antigens by Cells in Mouse and Human Primary and Secondary Follicles.- Localization Patterns of Germinal Center Cell Subsets Differing in Density and in Sedimentation Velocity.- Surface Phenotype and Migratory Capability of Peyer’s Patch Germinal Center Cells.- Separation and Characterization of Tonsillar Germinal Centre Lymphocytes Using Peanut Lectin.- Non-lymphoid Cells from Rat Intentinal Lymph.- Effect of Immunological Adjuvants on the Appearance of Monocyte and Dendritic Cell Precursors in Rat Thoracic Duct Lymph.- Dendritic Reticulum Cell Sarcoma: A Rare Tumor of the Follicular Compartment.- Immunoperoxidase Analysis of B and T Cell Populations in Human Lymphoid Follicles.- Disparity Between Humoral Antibody Formation and Proliferative Reactions in Lymph Nodes: C57L/J vs. Haired and Hairless HRS/J Mice.- Isolation and Properties of Spleen Follicular Dendritic Cells.- Immunocytological Characterization of the Constituent Cells of the Secondary Nodules in Human Tonsils-II.- Lymph Macrophages Enter the Germinal Center of Regional Lymph Nodes.- Formation of Germinal Centers in the Rat Thymus.- Maturity of Precursor Cells for Germinal Centers.