Armand Zini,
Ashok Agarwal
Springer New York
2013e druk, 2013
9781461484585
Sperm Chromatin for the Researcher
A Practical Guide
Specificaties
Paperback, 438 blz.
|
Engels
Springer New York |
2013e druk, 2013
ISBN13: 9781461484585
Rubricering
Levertijd ongeveer 8 werkdagen
Samenvatting
This concise, truncated version of Zini and Agarwal's Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction offers select, research-oriented chapters for a handy, more affordable, state-of-the-art resource. Sperm Chromatin for the Researcher addresses such vital issues as:
- Structure and function of human sperm chromatin
- Biological determinants of sperm chromatin damage
- Laboratory evaluation of sperm chromatin
- Protocols to measure sperm chromatin damage
Ideal for novice and experienced researchers alike, Sperm Chromatin for the Researcher contains all of the need-to-know information about these cutting-edge topics in reproductive medicine.
Specificaties
ISBN13:9781461484585
Taal:Engels
Bindwijze:paperback
Aantal pagina's:438
Uitgever:Springer New York
Druk:2013
Inhoudsopgave
<p>Part I: Human Sperm Chromatin: Structure and Function.- Sperm Chromatin: An Overview.- Sperm Nucleoproteins.- The Relationship Between Chromatin Structure and DNA Damage in Mammalian Spermatozoa.- Chromosome Positioning in Spermatozoa.- Sperm Mitochondrial DNA.- The Sperm Epigenome.- RNA Expression in Male Germ Cells During Spermatogenesis (Male Germ Cell Transcriptome).- Part II: Biological Determinants of Sperm Chromatin Damage.- Spermatogenesis: An Overview.- Role of Oxidative Stress in the Etiology of Sperm DNA Damage.- Abortive Apoptosis and Sperm Chromatin Damage.- Spermiogenesis in Sperm Genetic Integrity.- Part III: Laboratory Evaluation of Sperm Chromatin.- Sperm Chromatin Structure Assay (SCSA®): 30 Years of Experience with the SCSA®.- Sperm Chromatin Dispersion Test: Technical Aspects and Clinical Applications.- Basic and Clinical Aspects of Sperm Chromomycin A3 Assay.- Cytochemical Tests for Sperm Chromatin Maturity.- Acridine Orange Test for Assessment of Human Sperm DNA Integrity.- Laboratory Evaluation of Sperm Chromatin: TUNEL Assay.- Basic and Clinical Aspects of Sperm Comet Assay.- Assays Used in the Study of Sperm Nuclear Proteins.- Sperm Epigenetic Profile.- Clinical Significance of Sperm RNA.- Part IV: Protocols and Integrity Tests.- Sperm Chromatin Structure Assay (SCSA®).- Measurement of DNA Damage in Spermatozoa by TUNEL Assay.</p>