Biomarkers in Oncology

Prediction and Prognosis

Specificaties
Paperback, 447 blz. | Engels
Springer New York | 2013e druk, 2013
ISBN13: 9781461483151
Rubricering
Springer New York 2013e druk, 2013 9781461483151
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Samenvatting

This integrated book covers the entire spectrum of cancer biomarkers in development and clinical use. Predictive and prognostic markers are explored in the context of colon cancer, breast cancer, lung cancer, prostate cancer, and GIST. International experts provide insight into toxicity markers and surrogate markers. Attention is also given to biomarker assay development, validation, and strategies.

A powerful tool for determining decisions on therapy, selecting drug regimens, monitoring the efficacy of treatment, and performing individualized surveillance, biomarkers represent the forefront of cancer research and treatment. As these technologies become increasingly available for clinical use, this book will be an essential resource for oncologists and translational researchers.

Specificaties

ISBN13:9781461483151
Taal:Engels
Bindwijze:paperback
Aantal pagina's:447
Uitgever:Springer New York
Druk:2013

Inhoudsopgave

<p>Ch. 1: Predictive Markers in Colon Cancer</p><p>Armin Gerger, Melissa J. LaBonte, and Heinz-Josef Lenz</p><p> </p><p>Ch. 2: Prognostic Markers in Breast Cancer</p><p>Agustin A. Garcia, and Nazish Ahmad</p><p> </p><p>Ch. 3: Predictive Markers in Lung Cancer</p><p>Stephen V. Liu, and Barbara J. Gitlitz</p><p> </p><p>Ch. 4: Prostate Cancer: Predictive Markers in Clinical Development</p><p>Courtney K. Phillips, and Daniel P. Petrylak</p><p> </p><p>Ch. 5: Biomarkers in GIST</p><p>Howard J. Lim, and Charles D. Blanke</p><p> </p><p>Ch. 6: Cytogenetic and Molecular Aberrations as Predictive Biomarkers in Acute Myeloid Leukemia</p><p>Steffen Heeg, and Cornelius F. Waller</p><p> </p><p>Ch. 7: Prognostic Markers in Colon Cancer</p><p>Janine M. Davies, and Howard L. McLeod</p><p> </p><p>Ch. 8: Markers in Lung Cancer</p><p>Edwin Y. Lin, Ravin Rupani, and Barbara J. Gitlitz</p><p> </p><p>Ch. 9: Molecular Markers of Prostate Cancer Outcome</p><p>David Ian Quinn, and Gregory P. Swanson</p><p> </p><p>Ch. 10: Prediction of Chemotherapy Toxicities</p><p>Pierre Laurent-Puig, Thierry Lecomte, Marie-Anne Loriot, Valerie Boige, and Helene Blons</p><p> </p><p>Ch. 11: Surrogate Markers—The Role of Positron Emission Tomography Scanning</p><p>Derek G. Power, and David H. Ilson</p><p> </p><p>Ch. 12: Circulating Tumor Cells as Biomarkers</p><p>Amir Goldkorn, Tong Xu, and Stephen V. Liu</p><p> </p><p>Ch. 13: Focus on Personalized Molecular Based Medicine</p><p>Lex HT Van der Ploeg, Bud Mishra, Casimir P. Eitner, Jon Burrows, Thomas Wray Tombler, Jr., Vladimir Poponin, Dan J. Knauer, Ilia Ichetovkin, Richard M. Pinnola, Gregory A. Endress, and Patrick Soon-Shiong</p><p> </p><p>Ch. 14: Clinical Validation of Biomarkers</p><p>Sumithra J. Mandrekar, and Daniel Sargent</p><p> </p><p>Ch. 15: Regulatory Issues</p><p>Maxwell T. Vergo, and Al B. Benson III</p><p> </p><p>Ch. 16: Biomarkers for Safety Assessment and Clinical Pharmacology</p><p>Stan Louie, and Jared Russell</p><p> </p><p>Ch. 17: Biomarker Discovery Strategies: DNA, RNA and Protein</p><p>Eduardo Vilar, and Josep Tabernero</p><p> </p><p>Ch. 18: Biomarkers For Go/No Go Decisions</p><p>Ben Markman, and Josep Tabernero</p><p><p> </p>

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