Constantinos Koumenis,
Ester Hammond,
Amato Giaccia
Springer New York
2014e druk, 2013
9781461459149
Tumor Microenvironment and Cellular Stress
Signaling, Metabolism, Imaging, and Therapeutic Targets
Specificaties
Gebonden, 290 blz.
|
Engels
Springer New York |
2014e druk, 2013
ISBN13: 9781461459149
Rubricering
Onderdeel van serie
Advances in Experimental Medicine and Biology
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.
Specificaties
ISBN13:9781461459149
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:290
Uitgever:Springer New York
Druk:2014
Inhoudsopgave
Introduction.- Hypoxia and metabolism in cancer.- Hypoxia and Regulation of Cancer Cell Stemness.- Hypoxia-mediated metastasis.- Escape Mechanisms from Antiangiogenic Therapy: An Immune Cell’s Perspective.- Hypoxic VDAC1: a potential mitochondrial marker for cancer therapy.- Hypoxia directed drug strategies to target the tumor microenvironment.- Radiotherapy and the Tumor Microenvironment: Mutual Influence and Clinical Implications.- Autophagy and cell death to target cancer cells: exploiting synthetic lethality as cancer therapeutic.- Intratumoral Hypoxia as the Genesis of Genetic Instability and Clinical Prognosis in Prostate Cancer.- miR-210: Fine-Tuning the Hypoxic Response.- The role of complement in tumor growth.- Imaging angiogenesis, inflammation and metastasis in the tumor microenvironment with magnetic resonance imaging.- Index.