Stephen T. Sonis,
Dorothy M. Keefe
Springer New York
2013e druk, 2013
9781461454373
Pathobiology of Cancer Regimen-Related Toxicities
Specificaties
Gebonden, 292 blz.
|
Engels
Springer New York |
2013e druk, 2013
ISBN13: 9781461454373
Rubricering
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
The contents of this book will be organized into three sections. The first section defines the scope, impact and behaviour of cancer regimen-related toxicities and frames the issue of balancing treatment success and physiological cost. In the second segment of the book, the most current thinking around the pathobiology of specific, common, and representative toxicities is presented by leading researchers and translational scientists. The final portion of the book discusses the common biological relationships between toxicities, bioinformatical approaches to analysing key and common pathways, and strategies for the development of effective interventions.
Specificaties
ISBN13:9781461454373
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:292
Uitgever:Springer New York
Druk:2013
Inhoudsopgave
Preface.-Epidemiology and outcomes of regimen-related toxicities.- The biological basis for differences in normal tissue response to radiation therapy and strategies to establish predictive assays for individual complication risk.- The bystander effect: Ionizing radiation-induced non-targeted effects: Evidence, mechanism and significance.- The role of genes on the metabolism of chemotherapeutic agents and their impact on toxicity.- Animal models of regimen-related toxicities.- Nausea and Vomiting.- Mucositis.- Dermatitis and Alopecia.- Fibrosis.- Myelosuppression.- Neuropathy.- Fatigue.- Xerostomia.- Osteonecrosis.- Conclusions and therapeutic opportunities.- Index.