Derek LeRoith
Springer US
2012e druk, 2011
9781461405979
Insulin-like Growth Factors and Cancer
From Basic Biology to Therapeutics
Specificaties
Gebonden, 284 blz.
|
Engels
Springer US |
2012e druk, 2011
ISBN13: 9781461405979
Rubricering
Onderdeel van serie
Cancer Drug Discovery and Development
Levertijd ongeveer 8 werkdagen
Samenvatting
The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.
Specificaties
ISBN13:9781461405979
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:284
Uitgever:Springer US
Druk:2012
Inhoudsopgave
Preface.- Epidemiology of IGF-1 and Cancer.- Aging and Cancer: The IGF-I Connection.- Obesity, Type 2 Diabetes and Cancer.- IGF System and Breast Cancer.- The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression.- Mouse Models of IGF-1 Deficiency.- Insulin-like Growth Factor Signaling in Pediatric Sarcomas.- Cancer Genes, Tumor Suppressors, and Regulation of IGF-1R Expression in Cancer.- Mouse Models of IGF-1R and Cancer.- Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy.- Targeting Insulin-like Growth Factor (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer.- Calories and Cancer: The Role of Insulin-like Growth Factor.- Cancer Cell Metabolism.- Overlaps between the Insulin and IGF-1R and Cancer.- Index