The Acth Axis: Pathogenesis, Diagnosis and Treatment

Specificaties
Paperback, 338 blz. | Engels
Springer US | 0e druk, 2012
ISBN13: 9781461351085
Rubricering
Springer US 0e druk, 2012 9781461351085
Onderdeel van serie Endocrine Updates
€ 183,99
Levertijd ongeveer 8 werkdagen

Samenvatting

"In this outstanding volume, Dr. Gaillard has assembled a team of international experts who have written one of the most comprehensive treatises on this topic. Ranging from fundamental molecular developmental mechanisms of the corticotroph cell, to the treatment of Cushing's Disease, these chapters provide a cutting edge overview of the pathogenesis, diagnosis and treatment of disordered hypothalamic-pituitary-adrenal function. Especially noteworthy are the inclusion of chapters on appetite control and neuro-immunomodulation, reflecting the recent exciting advances in these fields.
The student of Cushing's Disease and the HPA axis will find elucidation of the latest basic scientific advances, coupled with patient friendly guidelines for clinical diagnosis and management of an extremely challenging neuroendocrine disorder. The repute of the authors, highest quality writing, lucid text and comprehensive coverage of the topics, all blend to result in an excellent text."

Specificaties

ISBN13:9781461351085
Taal:Engels
Bindwijze:paperback
Aantal pagina's:338
Uitgever:Springer US
Druk:0

Inhoudsopgave

1. Ontogeny of the pituitary corticotroph system.- 2. Proopiomelanocortin gene expression in man.- 3. Multifactorial regulation of the corticotroph axis: animal models.- 4. CRH-receptors and their ligands.- 5. ACTH precursors in different pathological conditions.- 6. Interactions between the hypothalamo-pituitary-adrenal axis and the immunological system.- 7. Pituitary corticotroph SOCS-3: an important regulator of POMC gene expression.- 8. The melanocortin pathway and food intake.- 9. The ACTH receptor and its mutations.- 10. Leptin and the hypothalamo-pituitary-adrenal axis.- 11. Cushing’s syndrome due to aberrant adrenal hormone receptors.- 12. Cushing’ s syndrome - The diagnosis and diffrential diagnosis.- 13. Lost and found: The pars intermedia of the human pituitary and its role in the histogenesis of silent “corticotroph” adenomas.- 14. Therapeutic strategies in Cushing’ s disease.- 15. Syndromes of glucocorticoid resistance.
€ 183,99
Levertijd ongeveer 8 werkdagen

Rubrieken

    Personen

      Trefwoorden

        The Acth Axis: Pathogenesis, Diagnosis and Treatment