Atherosclerosis V

Plenary Session: Cardiovascular Surgery (Co-Chairpersons: E. S. Crawford, D. C. Sabiston Jr.).- Atherosclerosis: Patterns and Rates of Progression.- Surgery for Coronary Artery Disease.- Review of 30 Years of Surgery of the Heart and the Great Vessels.- Mechanism of Progress. Page from the History of Cardiovascular Surgery.- Workshop: Coronary Bypass Surgery (Co-Chairpersons: M. E. DeBakey, J. W. Hurst).- My Current Views Regarding Coronary Bypass Surgery.- Results of Coronary Bypass: A Long-Term Perspective.- Current Views Regarding Coronary Bypass Surgery.- Comparison of Medical and Surgical Mortality in a High Risk Subset of Coronary Patients with Extreme Degrees of Exercise-Induced Ischemia.- Workshop: Epidemiology of Atherosclerotic Lesions (Co-Chairpersons: Y. Goto, J. P. Strong).- to Epidemiology of Atherosclerotic Lesions.- Epidemiology of Coronary Atherosclerosis: Postmortem vs Clinical Risk Factor Correlations. The Framingham Study.- Risk Factors for Coronary and Cerebral Atherosclerosis in the Oslo Study.- Atherosclerosis and Its Risk Factors Among Hawaii Japanese.- Atherosclerosis, Smoking and Other Risk Factors.- Workshop: Drug Treatment of Hyperlipidemia (Co-Chairpersons: D. Kritchevsky, R. Paoletti).- Drug Treatment of Hyperlipidemias.- Drug Treatment of Type II Hyperlipoproteinemia. Effects on Plasma Lipid and Lipoprotein Levels.- Synergism in Drug Treatment of Familial Hypercholesterolemia.- Effect of Plasma Lipoextraction and Infusion of Heterologous HDL on the Development of Experimental Atherosclerosis in Rabbits.- New Drug Treatments in Hyperlipidaemia.- Apoprotein Changes Following Treatments with Hypolipidemic Drugs.- Workshop: The Arterial Wall—I (Co-Chairpersons: M. D. Haust, K. W. Walton).- Milieu and Function of Arterial Wall—The Clues to Unique Reactivity.- Atherogenetic Factors Intrinsic to the Artery Wall.- Arterial Endothelium in the Initial Stages of Atherogenesis.- Ultrastructure of the Normal Arterial Endothelium and Intima.- Biochemical Studies on Permeability and the Interaction Between Blood Constituents and Arterial Components in Atherosclerosis.- Smooth Muscle Cells in Atherosclerosis.- Mononuclear Phagocytes in Atherosclerosis.- Altered Permeability in Atherosclerosis—Morphological Evidence.- The Elastic Element in the Arterial Wall: Biosynthesis and Degradation.- Prostacyclin Production by Vascular Smooth Muscle and Endothelial Cells.- Workshop: Lipid, Apoprotein and Lipoprotein Origin and Synthesis (Co-Chairpersons: R. J. Havel, B. Lewis).- Lipid, Apoprotein and Lipoprotein Origin and Synthesis.- Origin in Plasma of Low Density and High Density Lipoproteins.- Biological and Biochemical Aspects of ML-236B (Compactin) and Monacolin K, Specific Competitive Inhibitors of 3-hydroxy-3-methylglutaryl Coenzyme A Re-ductase.- Biosynthesis of Rat Apolipoprotein E.- Apoprotein Secretion from the Human Intestine.- Nascent VLDL and Nascent HDL from Liver.- Synthesis and Secretion of Very Low Density Lipoprotein by Cultured Rat Hepatocytes.- Workshop: Lipoprotein Structure (Co-Chairpersons: H. B. Brewer, Jr. W. Stoffel.- Topochemical Studies on Human High Density Lipoprotein.- The Associating System of Small Subunits in ApoLDL.- Lipoprotein Structure and the Mechanism of Action of Lipoprotein Lipase.- Structure of High Density Lipoproteins.- Cholesteryl Ester-Rich Very Low Density Lipoproteins: Magnetic Resonance Studies.- Plenary Session: Dietary Prevention of Coronary Heart Disease (Co-Chairpersons: R. I. Levy, G. Schettler.- Dietary Prevention of Coronary Artery Disease—A Policy Overview.- Dietary Prevention of Coronary Heart Disease.- Evaluation of the Evidence Relating National Dietary Patterns to Disease.- Diet-Lipid-Atherosclerosis Relationship: Epidemiological Evidence and Public Health Implications.- Dietary Prevention of Coronary Heart Disease: The Role of Essential Fatty Acids.- Workshop: Hyperlipidemia: Prevalence and Inheritance (Co-Chairpersons: H. A. Eder, J. Slack.- Identification of Children Who Are Heterozygotes for Familial Hypercholesterolaemia.- Lipoprotein and Apoprotein, Adipose Tissue and Hepatic Lipoprotein Lipase Levels in Patients with Familial Hyperchylomicronemia and Their Immediate Family Members.- Studies of a Large French-Canadian Kindred with Two Forms of Hyperlipoproteinemia.- The Complex Genetics of Type III Hyperlipoproteinemia: Influence of Co-inherited Monogenic Hyperlipidemia upon the Phenotypic Expression of Apolipoprotein E3 Deficiency.- Prevalence of Hyperlipoproteinemia in Selected North American Populations.- Hypercholesterolemia Type IIa: Incidence of Secondary, of Familial and of Non-Familial Forms in Central Europe.- Workshop: Risk Factors in Children (Co-Chairpersons: G. S. Berenson, M. J. Jesse).- Clues to Mechanisms of Cardiovascular Disease from an Epidemiologic Study of Children—The Bogalusa Heart Study.- Cigarette Smoking: A Risk Factor for Atherosclerosis in Childhood?.- Nutrient Intake, Lipids, and Lipoproteins in 6–19 Year Old Schoolchildren.- Pediatric Lipoprotein Metabolism and Atherosclerosis: A Prospectus.- Tracking of Coronary Risk Factors in Children: The Muscatine Study.- Risk Factors in Children: Role of Hereditary Hyperlipoproteinemia.- Workshop: Diet Treatment of Atherosclerosis (Co-Chairpersons: W. E. Connor, I. D. Frantz, Jr.).- Diet Treatment of Atherosclerosis.- Body Weight, Dietary Fat, Hyperlipidemia, and Coronary Heart Disease.- Effects of Dietary Fiber on Serum Lipids and Cholesterol Metabolism in Man.- Effects of Dietary Changes on Plasma Lipoprotein Lipids.- Hypolipidemic Diets and Biliary Lipid Composition.- Workshop: Immunology (Co-Chairpersons: J. D. Mathews, C. R. Minick).- Interaction of Genetic and Environmental Factors Causing Atherosclerosis by Immunologic Mechanisms.- Immunologic Arterial Injury and Atherogenesis.- Autoimmune Hyperlipidemia and Autoimmune Xanthomatosis.- Tobacco, Immunologic Injury, and Cardiovascular Disease.- Immunoregulatory Lipoproteins, Viral Hepatitis, and Cancer.- Regulation of Pathways of Lymphocyte Differentiation by the Serum Lipoprotein: LDL-In.- Autoimmune Mechanisms in the Development of Atherosclerosis.- Workshop: Animal Models (Co-Chairpersons: T. B. Clarkson, H.C. McGill).- Nutritional Factors in Atherosclerosis.- Cholesterol-Induced Hyperlipoproteinemia and Atherosclerosis in Dogs, Swine and Monkeys: Models for Human Atherosclerosis.- Dietary Animal Models for Studying Cardiovascular Disease Risk Factors.- Transformation of Naturally Occurring Quiescent Intimal Smooth Muscle Cell Masses into Atherosclerotic Lesions in Swine Fed a Hyperlipidemic Diet.- Reversal of Atherosclerosis: Comparison of Non-Human Primate Models.- Workshop: Enzymes of Lipoprotein Metabolism (Co-Chairpersons: J. A. Glomset, K. R. Norum.- Triglyceride Hydrolysis by Lipoprotein Lipase Bound to Endothelial Cells in Culture.- LDL-mediated Endocytosis and Cholesteryl Ester Transfer—Alternative Metabolic Pathways for the Regulation of Cellular Cholesterol Synthesis.- Mode of Action of the Hepatic Endothelial Lipase: Recycling Endocytosis via Coated Pits.- Lipoprotein Lipase and Hepatic Endothelial Lipase are Key Enzymes in the Metabolism of Plasma High Density Lipoproteins, Particularly of HDL2.- How Does Lipoprotein Lipase Bind to Substrate Lipoproteins and How Is Its Activity Regulated?.- Activation of Lipoprotein Lipase by Synthetic Fragments of ApoC-II.- Plenary Session: The Vessel Wall in Atherosclerosis (Co-Chairpersons: J. F. Mustard, R. W. Wissler).- The Vessel Wall and Atherosclerosis.- The Artery Wall and the Pathogenesis of Progressive Atherosclerosis.- Endothelial Dysfunction and the Pathogenesis of Atherosclerosis.- Prostacyclin and Thromboxane A2 in Platelet Vessel Wall Interactions.- The Platelet-Derived Growth Factor.- Workshop: Non-Dietary, Non-Pharmacological Treatment of Hyperlipidemia (Co-Chairpersons: T. E. Starzl, G. R. Thompson).- Portacaval Shunt for Type II Hyperlipidemia.- Combined Medico-Surgical Strategy for Severe Familial Hypercholesterolaemia.- Plasma Exchange in the Treatment of Familial Hypercholesterolemia.- Partial Heal Bypass: A Test of the Lipid-Atherosclerosis Hypothesis.- Selective Removal of Low Density Lipoproteins from Blood by Affinity Chromatography.- Comparison of Cholestyramine, Heal By-Pass and Portacaval Shunt in the Treatment of Familial Hypercholesterolemia.- Homozygous Hypercholesterolemia; Treatment by Portacaval Shunt.- Workshop: HDL: Negative Risk Factor for Coronary Heart Disease (Co-Chairpersons: W. P. Castelli, F. H. Epstein).- High Density Lipoproteins: An Overview.- Role of HDL in Individual Prediction and Community Prevention of Coronary Heart Disease.- Cross-Cultural, Ethnic, Demographic, and Environmental Factors Affecting High Density Lipoprotein Cholesterol and Their Mutual Interrelationships with Coronary Heart Disease.- Epidemiology and High Density Lipoproteins.- HDL Cholesterol, Tissue Cholesterol and Coronary Atherosclerosis: Epidemiological Correlations.- Workshop: Clinical Trials (Co-Chairpersons: W. T. Friedewald, J. Stamler).- The Multiple Risk Factor Intervention Trial.- Test of the Lipid Hypothesis: The Coronary Primary Prevention Trial (CPPT) of the Lipid Research Clinics Program.- The Chicago Heart Health Curriculum Program.- Workshop: The Arterial Wall—II (Co-Chairpersons: D. M. Small, E. B. Smith).- Summary of Concepts Concerning the Arterial Wall and Its Atherosclerotic Lesions.- Transport of Macromolecules Across the Artery Wall.- Cholesteryl Ester-Rich Lipid Inclusions in the Development of Experimental Atherosclerosis in Rabbits.- Low Density Lipoproteins in the Aorta: Relation to Atherosclerosis.- Cyclic Nucleotides and Atherosclerosis.- Differences in the Metabolism of Abnormal Atherogenic Low Density Lipoproteins from Cholesterol-Fed Nonhuman Primates by Cells in Culture.- Workshop: Vessel Wall—Platelet Interaction (Co-Chairpersons: H. R. Baumgartner, G. V. R. Born).- Factor VIII/Willebrand Factor and the Interaction of Blood Platelets with Subendothelium.- Do Platelets Contribute to Atherogenesis?.- Platelet and Endothelial Alterations in Experimental Arteriosclerosis.- Endothelium in Experimental Atherosclerosis.- Smooth Muscle Cell Kinetics In Vivo: A Comparative Study.- Workshop: Catabolism of Lipids, Apolipoproteins and Lipoproteins (Co-Chairpersons: D. S. Goodman, P. J. Nestel).- Turnover and Metabolism of Body Cholesterol in Humans.- Turnover of Very Low Density Lipoprotein Proteins.- Low Density Lipoprotein Metabolism in Familial Hypercholesterolemia.- Metabolism of Very Low Density Lipoprotein-Triglyceride in Man.- Effects of Drugs on High Density Lipoprotein Metabolism.- Liver and Cholesteryl Ester Transfer Amongst Lipoprotein—One Suggested Model.- Role of Chylomicrons in Atherogenesis.- Relationship Between the Properties of the Apo B Containing Low-Density Lipoproteins (LDL) of Normolipidemic Rhesus Monkeys and their Mitogenic Action on Arterial Smooth Muscle Cells Grown In Vitro.- Lipoprotein Structure and Metabolism: Inhomogeneity, Variability and Species Specificity.- Structure and Function of the Human Plasma Apolipoproteins.- Enzymatic Regulation of Lipoprotein Catabolism.- Cholesterol Feeding: Effects on Lipoprotein Structure and Metabolism.- Metabolism of Plasma Lipoproteins.- Workshop: Mutants Affecting Lipoproteins and Apoproteins (Co-Chairpersons: G. Assmann, J. A. Little).- Possible Mechanisms of Lipid Storage in Tangier Disease.- to Deficiencies of Apolipoproteins CII and EIII With Some Associated Clinical Findings.- Apolipoprotein CII Deficiency.- Tangier Disease.- Abetalipoproteinemia and Hypobetalipoproteinemia: Questions Still Exceed Insights.- Polymorphism of Apolipoprotein E.- Workshop: Hypertension (Co-Chairpersons: J. M. Laragh, J. R. Mitchell).- Renin Sodium Profiling and Vasoconstriction Volume Analysis of Hypertensive Patients. A New Era for Diagnosis and Treatment.- Aortic Endothelial Changes During the Development and Reversal of Experimental Hypertension.- Atherosclerosis and Its Risk Factors in Japan.- Controlled Therapeutic Trial in Mild Hypertension—Initial Results.- Clinical and Pathogenic Relevance of Erythrocyte Cation Fluxes Measurement in Human Hypertension.- Workshop: Regression (Co-Chairpersons: D. H. Blankenhorn, J. P. Strong).- Estimated Rates of Progression and Regression of Human Femoral and Coronary Atherosclerosis in 45-Year-Old Men.- Community Pathology of Atherosclerosis and Coronary Heart Disease in New Orleans: Relationship of Risk Factors to Atherosclerotic Lesions.- Regression Sequences After Experimental Atherosclerosis.- Changes in Atherosclerotic Lesions Following Surgical Cholesterol Reduction.- Approaches to the Study of Atherosclerosis Regression in Rhesus Monkeys: Interpretation of Morphometric Measurements of Coronary Arteries.- Regression of Advanced Atherosclerotic Lesions in Swine.- Differences in the Degradation-Rate of Intracellular Lipid Droplets in the Intimal Smooth Muscle Cells and Macrophages of Regressing Atherosclerotic Lesions of Primates.- Quantitating Rhesus Monkey Atherosclerosis Progression and Regression with Time.- Workshop: The Interrelationship Between Lipid and Prostaglandin Metabolism (Co-Chairpersons: S. Bergstrom, G. S. Boyd).- Prostacyclin and Atherosclerosis—A Hypothesis.- Modulation by Prostaglandins of Vascular Reactivity to Adrenergic Stimuli.- Prostaglandins, Thrombin Receptors and Platelet Aggregation in Normal and Hyper-cholesterolemic Subjects.- Prostaglandins, Thromboxanes and Leukotrienes.- Workshop: Cellular Metabolism of Lipoproteins (Co-Chairpersons: E. L. Bierman, N. Myant.- Role of Hormones Associated with Atherogenesis in Modulating Cellular Metabolism of Lipoproteins.- Platelet Production of Pathological LDL.- Modulation of Cellular Cholesterol Metabolism by LCAT Treated Lipoproteins.- Deposition and Hydrolysis of Cytoplasmic Triglyceride and Cholesterol Ester in Aortic Smooth Muscle Cells in Culture.- The Role of the Liver in LDL Catabolism.- Workshop: Apoprotein Quantification (Co-Chairpersons: P. Alaupovic, D. Seidel).- Standardization of Apolipoprotein Immunoassays by an Isotope Dilution Method.- Rate-Nephelometry of A-I and Electrophoresis.- Methodological Considerations in Apolipoprotein Immunoassay.- Plasma Levels of Some Apolipoproteins in Human Atherosclerosis.- Quantitation of C Apolipoprotein Metabolism in Human Subjects.- Quantitation of Apolipoproteins C-II and C-III in Plasma.