<p>Contents</p> <p>Preface vii</p> <p>Contributors ix</p> <p>Acknowledgments xv</p> <p>SECTION 1: Epidemiology and biology of HIV infection</p> <p>1 The global epidemiology of HIV/AIDS 3</p> <p>Irum Zaidi, Kevin M De Cock</p> <p>2 The origins and diversification of HIV 15</p> <p>Michael Worobey, Guan-Zhu Han</p> <p>3 Molecular biology of HIV: implications for new therapies 25</p> <p>Warner C Greene, B Matija Peterlin, Matthew H Stremlau</p> <p>4 The immune response to HIV 45</p> <p>Clive M Gray, Pamela Gumbi, Lycias Zembe, Mopo Radebe, Bruce Walker</p> <p>5 Viral and host determinants of HIV-1 disease progression 59</p> <p>Danie¨lle van Manen, Ange´lique B van ’t Wout, Hanneke Schuitemaker</p> <p>6 Acute HIV infection 77</p> <p>Anthony D Kelleher, David A Cooper</p> <p>7 Biology of HIV-1 transmission 89</p> <p>Julie Overbaugh</p> <p>SECTION 2: Prevention, diagnosis, and treatment of HIV infection</p> <p>8 The design of a global HIV vaccine 97</p> <p>Jerome H Kim, Nelson L Michael</p> <p>9 HIV prevention 113</p> <p>Salim S Abdool Karim</p> <p>10 Laboratory testing for HIV infection 123</p> <p>James C Shepherd, Oliver Laeyendecker, Thomas C Quinn</p> <p>11 Overview of antiretroviral therapy 133</p> <p>Susa Coffey, Paul A Volberding</p> <p>12 Development and transmission of HIV drug resistance 155</p> <p>Mark A Wainberg, Gerasimos J Zaharatos</p> <p>13 Pharmacology of antiretroviral drugs 169</p> <p>Concepta Merry, Charles W Flexner</p> <p>14 Complications resulting from antiretroviral therapy for HIV infection 177</p> <p>David Nolan, Simon Mallal, Peter Reiss</p> <p>SECTION 3: Diseases associated with HIV infection</p> <p>15 Oral complications of HIV infection 195</p> <p>John S Greenspan, Deborah Greenspan</p> <p>16 Ocular manifestations of AIDS 207</p> <p>James P Dunn</p> <p>17 Global HIV and dermatology 219</p> <p>Toby Maurer, Robert Michelleti</p> <p>18 Gastrointestinal disorders in HIV including diarrhea 237</p> <p>Marie-Louise C Vachon, Douglas T Dieterich</p> <p>19 Primary neurological manifestation of HIV/AIDS 249</p> <p>David B Clifford, Mengesha A Teshome</p> <p>20 Psychiatric barriers and the international AIDS epidemic 257</p> <p>Chiadi U Onyike, Andrew F Angelino,</p> <p>Glenn J Treisman</p> <p>21 Cardiovascular complications of HIV infection 267</p> <p>Rakesh K Mishra</p> <p>22 Endocrine complications of HIV infection 275</p> <p>Steven A Taylor, Carl Grunfeld,</p> <p>Morris Schambelan</p> <p>23 Renal complications of HIV infection 287</p> <p>Jula K Inrig, Lynda A Szczech,</p> <p>Trevor E Gerntholtz, Paul E Klotman</p> <p>24 Pneumocystis pneumonia 297</p> <p>Robert J Blount, J Lucian Davis,</p> <p>Laurence Huang</p> <p>25 Other HIV-related pneumonias 313</p> <p>John G Bartlett</p> <p>26 HIV-associated tuberculosis 325</p> <p>Leyla Azis, Edward C Jones-Lo´pez,</p> <p>Jerrold J Ellner</p> <p>27 Disseminated Mycobacterium avium complex and other atypical mycobacterial infections 349</p> <p>Mark A Jacobson</p> <p>28 Candida in HIV infection 359</p> <p>William G Powderly</p> <p>29 Cryptococcosis and other fungal infections</p> <p>(histoplasmosis and coccidioidomycosis)</p> <p>in HIV-infected patients 369</p> <p>Kathleen R Page, Richard E Chaisson,</p> <p>Merle Sande</p> <p>30 Infection due to Penicillium marneffei 389</p> <p>Thira Sirisanthana, Khuanchai Supparatpinyo</p> <p>31 AIDS-associated toxoplasmosis 397</p> <p>Pablo A Moncada, Jose G Montoya</p> <p>32 Hepatitis virus infections 411</p> <p>Marion G Peters, Monika Sarkar</p> <p>33 Bartonella infections in HIV-infected individuals 421</p> <p>Jane E Koehler</p> <p>34 Management of herpesvirus infections</p> <p>(cytomegalovirus, herpes simplex virus, and varicella-zoster virus) 433</p> <p>W Lawrence Drew, Kim S Erlich</p> <p>35 HIV-associated malignancies 455</p> <p>Ronald T Mitsuyasu</p> <p>36 STDs and syphilis 467</p> <p>Elysia Larson, Jeffrey D Klausner</p> <p>SECTION 4: Prevention and management</p> <p>37 Prevention of mother-to-child transmission of HIV-1 485</p> <p>Lynne M Mofenson</p> <p>38 Managing HIV infection in children and adolescents 509</p> <p>Elizabeth H Doby, Andrew T Pavia</p> <p>39 Special issues regarding women with HIV infection 521</p> <p>Ruth M Greenblatt, Monica Gandhi</p> <p>40 HIV disease among substance users:</p> <p>treatment issues 537</p> <p>R Douglas Bruce, Frederick L Altice,</p> <p>Gerald Friedland</p> <p>41 The HIV-infected international traveler 551</p> <p>Malcolm John</p> <p>Index 561</p>
