Section 1 Basic Considerations.- 1 Introduction and Definitions.- Difficulties in Definition.- The Hypersensitive Disorders of Micturition.- 2 Normal Sensation of the Lower Urinary Tract.- Description of Normal Sensation.- Anatomical and Physiological Considerations.- 3 Diagnostic Criteria of the Hypersensitive Disorders.- Sensation in the Hypersensitive Disorders.- Bacteriological Considerations in the Diagnosis of the Hypersensitive Disorders.- The Hypersensitive Disorders and Detrusor Contraction.- Conclusion.- 4 Examination and Investigation of Sensory Patients.- Cystometric Examination.- Electromyography.- Assessment of Anxiety.- Frequency/Volume Charts.- Assessment of Bladder and Urethral Sensation.- Microbiological Considerations.- Examination Under Anaesthetic.- Section 2 Interstitial Cystitis.- 5 Historical Perspective.- 6 Clinical Symptom Complex.- Techniques of Investigation.- Concluding Remarks—Value of Diagnostic Methods.- 7 Morphological Studies of the Bladder Wall in Interstitial Cystitis.- General Pathology.- Specific Pathology.- 8 Treatment of Interstitial Cystitis.- Treatment.- Summary.- Section 3 The Urethral Syndrome.- 9 Historical Review—Confusions in Definition.- 10 Microbiology of the Female Urethra and Adjacent Areas.- Microbiology of the Female Lower Genito-urinary Tract.- The Role of Potential Bladder Pathogens in the Urethral Syndrome.- The Role of Sexually Transmitted Organisms in the Urethral Syndrome.- Conclusions.- 11 Urethral Syndrome—Clinical Features.- Definition of Urethral Syndrome.- Incidence.- History.- Urethral Hypersensitivity and Allied Conditions.- Examination and Routine Investigation.- The Urge Syndrome.- 12 Structure of the Trigone and Urethra in the Urethral Syndrome.- Pseudo-membranous Trigonitis.- Urethral Morphology.- 13 Urethral Syndrome—Urodynamic Studies.- Urodynamic Observations.- 14 Treatment of the Urethral Syndrome.- General Measures.- Antibiotics.- Pharmacological and Surgical Treatment for the Urethral Syndrome.- Alternative Surgical Techniques.- Bladder Retraining.- Section 4 Prostatodynia.- 15 Inflammatory Prostatic Disease.- Investigation of the Patient.- Diagnostic Significance of Expressed Prostatic Secretion.- General Examination and Investigation of the Prostatitis Patient.- Aetiology of Prostatitis.- Aetiology of Non-bacterial Prostatitis.- Management of Patients with Prostatitis.- The Urinary Tract Infection Clinic.- 16 Prostatodynia—Clinical Aspects.- Aetiology of Prostatodynia.- Clinical Features.- The Anxious Bladder.- Examination and Investigation.- 17 Prostatodynia and Anxious Bladder—Urodynamic Aspects.- Urodynamic Observations.- Interpretation of Urodynamic Observations in Psychogenic Voiding Disorders.- Low Pressure/Low Flow Micturition and Detrusor-Sphincter Dyssynergia.- 18 Application of Psychological and Psychophysiological Methods in Prostatodynia.- Procedure.- Results.- Discussion.- 19 Treatment of Prostatodynia and the Psychogenic Voiding Disorders.- Non-specific Methods of Treatment.- Operative Treatment of Voiding Abnormalities.- Pharmacological Relaxation Therapy.- Summary.