Dried Blood Spots – Applications and Techniques

Applications and Techniques

Specificaties
Gebonden, 376 blz. | Engels
John Wiley & Sons | e druk, 2014
ISBN13: 9781118054697
Rubricering
John Wiley & Sons e druk, 2014 9781118054697
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This book covers the fundamentals, experimental procedures, and applications of dried blood spot (DBS) sampling in combination with various qualitative and quantitative analytical techniques. This includes sample collection, storage, transportation, and sample preparation for various analysis. Experimental examples in newborn screening, toxicokinetics and pharmacokinetics, and forensics are also given. Finally, the book provides an overview of trends in quantitative and qualitative analysis of DBS samples as well as future perspectives. This provides a valuable working guide to researchers, professionals, and students in healthcare, medical science, diagnosis, chemistry, and pharmaceuticals.

Specificaties

ISBN13:9781118054697
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:376

Inhoudsopgave

<p>PREFACE viii</p>
<p>CONTRIBUTORS x</p>
<p>PART I HISTORY, APPLICATIONS, AND HEALTHCARE</p>
<p>1 Overview of the History and Applications of Dried Blood Samples 3<br /> W. Harry Hannon and Bradford L. Therrell, Jr.</p>
<p>2 Dried Blood Spot Cards 16<br /> Brad Davin and W. Harry Hannon</p>
<p>3 Dried Blood Spot Sample Collection, Storage, and Transportation 21<br /> Joanne Mei</p>
<p>4 Dried Blood Spot Specimens for Polymerase Chain Reaction in Molecular Diagnostics and Public Health Surveillance 32<br /> Chunfu Yang</p>
<p>5 Application of Enzyme Immunoassay Methods Using Dried Blood Spot Specimens 40<br /> Mireille B. Kalou</p>
<p>6 Applications of Dried Blood Spots in Newborn and Metabolic Screening 53<br /> Donald H. Chace, Alan R. Spitzer, and V&iacute;ctor R. De Jes&uacute;s</p>
<p>7 Dried Blood Spots for Use in HIV–Related Epidemiological Studies in Resource–Limited Settings 76<br /> Sridhar V. Basavaraju and John P. Pitman</p>
<p>8 Use of Dried Blood Spot Samples in HCV–, HBV–, and Influenza–Related Epidemiological Studies 95<br /> Harleen Gakhar and Mark Holodniy</p>
<p>9 Applications of Dried Blood Spots in General Human Health Studies 114<br /> Eleanor Brindle, Kathleen A. O Connor, and Dean A. Garrett</p>
<p>10 Applications of Dried Blood Spots in Environmental Population Studies 130<br /> Antonia M. Calafat and Kayoko Kato</p>
<p>11 The Use of Dried Blood Spots and Stains in Forensic Science 140<br /> Donald H. Chace and Nicholas T. Lappas</p>
<p>PART II PHARMACEUTICAL APPLICATIONS</p>
<p>12 Pharmaceutical Perspectives of Use of Dried Blood Spots 153<br /> Christopher Evans and Neil Spooner</p>
<p>13 Punching and Extraction Techniques for Dried Blood Spot Sample Analysis 160<br /> Philip Wong and Christopher A. James</p>
<p>14 Considerations in Development and Validation of LC–MS/MS Method for Quantitative Analysis of Small Molecules in Dried Blood Spot Samples 168<br /> Wenkui Li</p>
<p>15 Challenges and Experiences with Dried Blood Spot Technology for Method Development and Validation 179<br /> Chester L. Bowen and Christopher A. Evans</p>
<p>16 Clinical Implications of Dried Blood Spot Assays for Biotherapeutics 188<br /> Matthew E. Szapacs and Jonathan R. Kehler</p>
<p>17 Potential Role for Dried Blood Spot Sampling and Bioanalysis in Preclinical Studies 195<br /> Qin C. Ji and Laura Patrone</p>
<p>18 Clinical and Bioanalytical Evaluation of Dried Blood Spot Sampling for Genotyping and Phenotyping of Cytochrome p450 Enzymes in Healthy Volunteers 202<br /> Theo de Boer, Izaak den Daas, Jaap Wieling, Johan Wemer, and LingSing Chen</p>
<p>19 Application of Dried Blood Spot Sampling in Clinical Pharmacology Trials and Therapeutic Drug Monitoring 216<br /> Kenneth Kulmatycki, Wenkui Li, Xiaoying (Lucy) Xu, and Venkateswar Jarugula</p>
<p>20 Automation in Dried Blood Spot Sample Collection, Processing, and Analysis for Quantitative Bioanalysis in Pharmaceutical Industry 229<br /> Leimin Fan, Katty Wan, Olga Kavetskaia, and Huaiqin Wu</p>
<p>21 Beyond Dried Blood Spots Application of Dried Matrix Spots 235<br /> Shane R. Needham</p>
<p>PART III NEW TECHNOLOGIES AND EMERGING APPLICATIONS</p>
<p>22 Direct Analysis of Dried Blood Spot Samples 245<br /> Paul Abu–Rabie</p>
<p>23 Paper Spray Ionization for Direct Analysis of Dried Blood Spots 298<br /> Jiangjiang Liu, Nicholas E. Manicke, R. Graham Cooks, and Zheng Ouyang</p>
<p>24 Direct Solvent Extraction and Analysis of Biomarkers in Dried Blood Spots Using a Flow–Through Autosampler 314<br /> David S. Millington, Haoyue Zhang, M. Arthur Moseley, J. Will Thompson, and Peter Smith</p>
<p>25 Development of Biomarker Assays for Clinical Diagnostics Using a Digital Microfluidics Platform 325<br /> David S. Millington, Ramakrishna Sista, Deeksha Bali, Allen E. Eckhardt, and Vamsee Pamula</p>
<p>26 Applications and Chemistry of Cellulose Papers for Dried Blood Spots 332<br /> Jacquelynn Luckwell, &Aring;ke Danielsson, Barry Johnson, Sarah Clegg, Mark Green, and Alan Pierce</p>
<p>27 Derivatization Techniques in Dried Blood Spot Analysis 344<br /> Ann–Sofie M.E. Ingels, Nele Sadones, Pieter M.M. De Kesel, Willy E. Lambert, and Christophe P. Stove</p>
<p>INDEX 355</p>

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