Edward J. Massaro
Humana Press
2002e druk, 2002
9780896039438
Handbook of Copper Pharmacology and Toxicology
Specificaties
Gebonden, 608 blz.
|
Engels
Humana Press |
2002e druk, 2002
ISBN13: 9780896039438
Rubricering
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
Edward J. Massaro and a panel of leading biomedical researchers and clinical practitioners review, in-depth, the status of our current knowledge concerning the biochemistry of copper in general and its role in health and disease in particular. Drawing on the wealth of new information emerging from the molecular biology revolution, these experts survey the most important research areas of copper pharmacology and toxicology, including copper proteins and transport, copper toxicity and therapeutics, and copper metabolism and homeostasis. They also discuss the molecular pathogenesis of copper in a variety of metabolic diseases, Menkes and Wilson's diseases and occipital horn syndrome, as well as the role of copper in Parkinson's disease, prion disease, familial amytrophic lateral sclerosis (ALS), and Alzheimer's disease.
Specificaties
ISBN13:9780896039438
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:608
Uitgever:Humana Press
Druk:2002
Inhoudsopgave
Part I. Copper in Mammals
Biochemistry and Molecular Biology of Copper in Mammals
Maria C. Linder
Part II. Copper Proteins
Biochemistry of the Wilson's Disease Protein
Svetlana Lutsenko, Ruslan Tsivkovskii, Matthew J. Cooper, Brian C. MacArthur, and Hans-Peter Bächinger
Biologically Relevant Properties of Copper-Containing Proteins Analyzed by Means of Semiquantitative and Quantitative Theoretical Descriptors, Francesca De Rienzo, R. Razif Gabdoulline, Rebecca C. Wade, and M. Cristina Menziani
Molecular Modeling and Dynamics of Copper Proteins
Mattia Falconi and Alessandro Desideri
The Prion Protein and Copper: What Is the Connection?
Lesley R. Brown and David A. Harris
Prion Protein: A Synaptic Cuproprotein
David R. Brown
Cytochrome-c Oxidase
Shinya Yoshikawa
The Fet3 Protein: A Multicopper Ferroxidase Essential to Iron Metabolism in Yeast
Daniel J. Kosman
Interaction of Copper-Binding Proteins from Enteroccus hirae
Paul A. Cobine, Christopher E. Jones, Wasantha A. Wickramasinghe, Marc Solioz, and Charles T. Dameron
Part III. Copper Transport
Copper Uptake in Eukaryotic Cells
Lisbeth Birk Møller and Nina Horn
The Role of PINA in Copper Transport, Circadian Rhythms, and Wilson's Disease
Jimo Borjigin, Xing Sun, and Michael M. Wang
The Identification of Motifs Involved in the Intracellular Trafficking of the Menkes Disease Protein
Michael J. Francis and Anthony P. Monaco
Intracellular Copper Transport and ATP7B, the Wilson's Disease Protein
Kunihiko Terada and Toshihiro Sugiyama
A Multicopper Oxidase-Based Iron-Transport System in Yeast
Jerry Kaplan
Part IV. Molecular Pathogenesis of Diseases of Copper Metabolism
Molecular Basis of Diseases of Copper Homeostasis
Julian F. B. Mercer, David Kramer, andJames Camakaris
Disturbances of Copper Homeostasis and Brain Function
Giuseppe Rotilio, Maria Rosa Ciriolo, Maria Teresa Carri, and Luisa Rossi
Role of Copper and Other Transition Metal Ions in the Pathogenesis of Parkinson's Disease, Prion Diseases, Familial Amytrophic Lateral Sclerosis and Alzheimer's Disease
Gerd Multhaup, Hermann H. Dieter, Konrad Beyreuther, and Thomas A. Bayer
Molecular Genetics and Clinical Aspects of Menkes Disease and Occipital Horn Syndrome
Hiroko Kodama
The Meaning of Alternative Transcripts of the Menkes Disease Gene
Edward D. Harris, Manchi C. M. Reddy, and Sudeep Majumdar
Expression Profiling in Menkes Disease
Zeynep Tümer, Nina Horn, and Lars Riff Jensen
Regulation by Copper of the Expression of Human Bis, a New Gene Involved in the Cellular Stress Response to Metals
Maria Gabriella Pagliuca, Rosa Lerose, and Arturo Leone
Non-Indian Childhood Cirrhosis: Using a Founder Population to Identify the Underlying Genetic Defect
Cisca Wijmenga
Part V. Copper Toxicity and Therapeutics
Biological Effects of Chronic Copper Exposure
Magdalena Araya, Mauricio González, Manuel Olivares, and Ricardo Uauy
Copper Toxicity to Tight Junctions in the Human Intestinal Caco-2 Cell Line
Simonetta Ferruzza, Yula Sambuy, Andrea Onetti-Muda, Fabio Nobili, and Maria Laura Scarino
Cellular Responses to Copper in Aquatic Organisms: Importance of Oxidative Stress and Alteration of Signal Transduction
Aldo Viarengo, Bruno Burlando, and Claudia Bolognesi
Selective Removal of Copper Accumulating in the Form Bound to Metallothionein by Tetrathiomolybdate
Kazuo T. Suzuki and Yasumitsu Ogra
Control of Copper in Wilson's Disease and Diseases of Neovascularization, such as Cancer
George J. Brewer
Copper-Rich Metallothionein Polymers During the Development of
Biochemistry and Molecular Biology of Copper in Mammals
Maria C. Linder
Part II. Copper Proteins
Biochemistry of the Wilson's Disease Protein
Svetlana Lutsenko, Ruslan Tsivkovskii, Matthew J. Cooper, Brian C. MacArthur, and Hans-Peter Bächinger
Biologically Relevant Properties of Copper-Containing Proteins Analyzed by Means of Semiquantitative and Quantitative Theoretical Descriptors, Francesca De Rienzo, R. Razif Gabdoulline, Rebecca C. Wade, and M. Cristina Menziani
Molecular Modeling and Dynamics of Copper Proteins
Mattia Falconi and Alessandro Desideri
The Prion Protein and Copper: What Is the Connection?
Lesley R. Brown and David A. Harris
Prion Protein: A Synaptic Cuproprotein
David R. Brown
Cytochrome-c Oxidase
Shinya Yoshikawa
The Fet3 Protein: A Multicopper Ferroxidase Essential to Iron Metabolism in Yeast
Daniel J. Kosman
Interaction of Copper-Binding Proteins from Enteroccus hirae
Paul A. Cobine, Christopher E. Jones, Wasantha A. Wickramasinghe, Marc Solioz, and Charles T. Dameron
Part III. Copper Transport
Copper Uptake in Eukaryotic Cells
Lisbeth Birk Møller and Nina Horn
The Role of PINA in Copper Transport, Circadian Rhythms, and Wilson's Disease
Jimo Borjigin, Xing Sun, and Michael M. Wang
The Identification of Motifs Involved in the Intracellular Trafficking of the Menkes Disease Protein
Michael J. Francis and Anthony P. Monaco
Intracellular Copper Transport and ATP7B, the Wilson's Disease Protein
Kunihiko Terada and Toshihiro Sugiyama
A Multicopper Oxidase-Based Iron-Transport System in Yeast
Jerry Kaplan
Part IV. Molecular Pathogenesis of Diseases of Copper Metabolism
Molecular Basis of Diseases of Copper Homeostasis
Julian F. B. Mercer, David Kramer, andJames Camakaris
Disturbances of Copper Homeostasis and Brain Function
Giuseppe Rotilio, Maria Rosa Ciriolo, Maria Teresa Carri, and Luisa Rossi
Role of Copper and Other Transition Metal Ions in the Pathogenesis of Parkinson's Disease, Prion Diseases, Familial Amytrophic Lateral Sclerosis and Alzheimer's Disease
Gerd Multhaup, Hermann H. Dieter, Konrad Beyreuther, and Thomas A. Bayer
Molecular Genetics and Clinical Aspects of Menkes Disease and Occipital Horn Syndrome
Hiroko Kodama
The Meaning of Alternative Transcripts of the Menkes Disease Gene
Edward D. Harris, Manchi C. M. Reddy, and Sudeep Majumdar
Expression Profiling in Menkes Disease
Zeynep Tümer, Nina Horn, and Lars Riff Jensen
Regulation by Copper of the Expression of Human Bis, a New Gene Involved in the Cellular Stress Response to Metals
Maria Gabriella Pagliuca, Rosa Lerose, and Arturo Leone
Non-Indian Childhood Cirrhosis: Using a Founder Population to Identify the Underlying Genetic Defect
Cisca Wijmenga
Part V. Copper Toxicity and Therapeutics
Biological Effects of Chronic Copper Exposure
Magdalena Araya, Mauricio González, Manuel Olivares, and Ricardo Uauy
Copper Toxicity to Tight Junctions in the Human Intestinal Caco-2 Cell Line
Simonetta Ferruzza, Yula Sambuy, Andrea Onetti-Muda, Fabio Nobili, and Maria Laura Scarino
Cellular Responses to Copper in Aquatic Organisms: Importance of Oxidative Stress and Alteration of Signal Transduction
Aldo Viarengo, Bruno Burlando, and Claudia Bolognesi
Selective Removal of Copper Accumulating in the Form Bound to Metallothionein by Tetrathiomolybdate
Kazuo T. Suzuki and Yasumitsu Ogra
Control of Copper in Wilson's Disease and Diseases of Neovascularization, such as Cancer
George J. Brewer
Copper-Rich Metallothionein Polymers During the Development of