Genetics of Cerebrovascular Disease
Samenvatting
This is the first book that focuses on genetics and stroke, an area of ever growing clinical and research importance. It integrates laboratory, applied and clinical research, with an emphasis on molecular genetic and genetic epidemiologic aspects of cerebrovascular disease.
Beginning with an overview of the key risk factors for stroke, most of the major stroke types and syndromes are detailed, as well as the key genetic advances for several stroke mechanisms and etiologies. The text also provides expert guidance for evaluating patients′ genetic stroke profile. Extensive bibliographies for each chapter further guide the reader to topics of particular interest.
As the pioneering text on this topic, Genetics of Cerebrovascular Disease should be of considerable interest and value to both clinicians and researchers in this area.
Specificaties
Inhoudsopgave
<p>Preface.</p>
<p>Part I. Genetic Principles and Techniques.</p>
<p>1. Genetic concepts and Techniques.</p>
<p>M.J. Alberts.</p>
<p>2. Genetic epidemiology and linkage.</p>
<p>M.C. Speer.</p>
<p>3. Molecular genetics and gene isolation.</p>
<p>M.J. Alberts.</p>
<p>.</p>
<p>Part II. Genetics of Risk Factors for Cerebrovascular Disease.</p>
<p>4. Genetics of hypertension.</p>
<p>L.P. Svetkey, E. O′Riordan, P.J. Conlon, O. Emovon.</p>
<p>5. Molecular Genetics of Lipid Metabolism.</p>
<p>C. Graffagnino.</p>
<p>6. Genetic of Atherosclerosis.</p>
<p>T.J. DeGraba.</p>
<p>7. Genetics of Coagulation Disorders.</p>
<p>T.L. Ortel.</p>
<p>.</p>
<p>Part III. Genetics of Specific Stroke Etiologies and Syndromes.</p>
<p>8. Genetic Epidemiology and Family Studies of Stroke.</p>
<p>L.M. Brass, M.J. Alberts.</p>
<p>9. Inherited Cardiac Diseases that Cause Stroke.</p>
<p>M.J. Alberts.</p>
<p>10. Vasculopathies.</p>
<p>H. Chabriat, E. Tournier–Lasserve, M–G. Bousser.</p>
<p>11. Intracerebral Hemorrhage and Vascular Malformations.</p>
<p>M.J. Alberts.</p>
<p>12. Subarachnoid Hemorrhage and Intracranial Aneurysms.</p>
<p>M.J. Alberts.</p>
<p>13. Genetic Causes of Pediatric Stroke.</p>
<p>P.I. Andrews, R.S. Kandt.</p>
<p>14. Inherited Systemic Disorders that Cause Stroke.</p>
<p>M.J. Alberts.</p>
<p>.</p>
<p>Part IV. Clinical Applications.</p>
<p>15. Evaluation of Stroke Patients for Inherited Causes of Stroke.</p>
<p>M.J. Alberts, J.M. Stajich.</p>
<p>16. Genetic Counseling.</p>
<p>S.M. Palmer.</p>
<p>17. Gene Therapy.</p>
<p>J.N. Lozier.</p>
<p>Index</p>