List of Principal Contributors. Preface. <strong>Section I: Cholestatic Liver</strong> <strong>Diseases: Physiology, Pathophysiology and Genetics.</strong> <strong>1.</strong> Adaptive Responses in Bile Salt Transport Proteins in Cholangiocytes and Kidney in a Rat Model of Obstructive Cholestasis; J. Lee, et al. <strong>2.</strong> Drug and Steroid Clearance by the Hepatic Organic Anion Transporting Protein Family; G.A. Kullak-Ublick, et al. <strong>3.</strong> Down-regulation and Inhibition of 11beta-Hydroxysteroid Dehydrogenase: Another Explanation for Sodium Retention and Ascites Formation in Bile Duct-Ligated Rats; J. Reichen, et al. <strong>4.</strong> The Role of Survival Signals in Bile Acid Modulation of Apoptosis; C. Rust, et al. <strong>5.</strong> Genetic Transport Defects as Causes of Cholestasis; P.L.M. Jansen, M. Müller. <strong>Section II:</strong> <strong>Cholestatic Liver Diseases: Pathogenesis and Treatment.</strong> <strong>6.</strong> Primary Biliary Cirrhosis: A Model Cholestatic Disease of Adults; M.E. Gershwin, et al. <strong>7.</strong> Non-alcoholic Steatohepatitis (NASH): Potential Causes and Pathogenic Mechanisms; D. Pessayre, et al. <strong>8.</strong> Current Therapeutic Approaches to Autoimmune Cholestatic Liver Disease; R. Poupon, R.E. Poupon. <strong>9.</strong> Mechanisms of Action of Ursodeoxycholic Acid in Cholestasis; U. Beuers. <strong>10.</strong> Endoscopic Treatment of Patients with Primary Sclerosing Cholangitis; A. Stiehl. <strong>Section III: Gallstone</strong> <strong>Disease.</strong> <strong>11.</strong> Functional and Genetic Studies of Abcc2 in Inbred Mice: Evidence for a Primary Role of the Canalicular Conjugate Organic Anion Transporter in Lith2-transmitted Cholesterol Gallstone Susceptibility; G. Bouchard, et al. <strong>12.</strong> Regulation of Biliary Lipid Secretion; A.K. Groen, R.P.J. Oude-Elferink. <strong>13.</strong> Pathogenesis and Clinical Relevance of Biliary Sludge; S.P. Lee, C.W. Ko. <strong>14.</strong> Treatment of Gallstone Disease &endash; Non-Surgical; M. Sackmann. <strong>15.</strong> Surgical Treatment of Gallstone Disease; G. Meyer, et al. <strong>Section IV: Liver Cirrhosis:</strong> <strong>Pathogenesis and Treatment of Portal Hypertension.</strong> <strong>16.</strong> Altered Function of Splanchnic Vasculature; D. Lebrec, R. Moreau. <strong>17.</strong> Liver Cirrhosis: Pathogenesis and Treatment of Portal Hypertension &endash; Role of Hepatic Stellate Cells; M. Pinzani. <strong>18.</strong> Pharmacotherapy of portal hypertension; J. Bosch. <strong>19.</strong> The Transjugular Intrahepatic Portosystemic Shunt for Treatment of Variceal Bleeding; M. Rössle. <strong>Section V: Liver Cirrhosis: Pathogenesis and Treatment of</strong> <strong>Ascites and Encephalopathy.</strong> <strong>20.</strong> Pathogenesis of Ascites and Hepatorenal Syndrome: Altered Haemodynamics and Neurohumoral Systems; M. Bernardi, P. Caraceni. <strong>21.</strong> Therapy of Ascites and Hepatorenal Syndrome: Novel Approaches; V. Gülberg, A.L. Gerbes. <strong>22.</strong> Spontaneous Bacterial Peritonitis, Treatment and Prophylaxis; P. Ginès, R. Ortega. <strong>23.</strong> Hepatic Encephalopathy; D. Häussinger, et al. <strong>Section VI: Viral Hepatitis: New Perspective</strong> <strong>on Pathogenesis and Molecular Virology.</strong><strong>24.</strong> Pathogenesis of Hepatitis C Virus Infection; H.M. Diepolder, et al. <strong>25.</strong> Viral Hepatitis and Hepatocellular Carcinoma; W.H. Caselmann. <strong>Section VII: Viral</strong> <strong>Hepatitis: Present and Future Perspectives in Therapy and Vaccine <strong>Development.</strong> <strong>26.</strong> Viral Hepatitis: The Molecular Approach; H.E. Blum, et al. <strong>27.</strong> Future Strategies in Hepatitis Therapy: The Immunological Approach; M.-C. Jung. <strong>Section VIII: Liver Transplantation: The Donor</strong> <strong>Organ.</strong> <strong>28.</strong> Mechanisms of Ischemia &endash; Reperfusion Injury; H. Jaeschke. <strong>29.</strong> Potential of Preconditioning; M. Bilzer, et al. <strong>30.</strong> Sinusoidal Endothelial Cell Injury During Hepatic Preservation and Reperfusion; P.-A. Clavien. <strong>31.</strong> Xeno-Transplantation &endash; the Future? E. Thein, C. Hammer. <strong>32.</strong> Split Livers and Living Donors &endash; Where do we Stand Today? M. Hertl, et al. <strong>Section IX: Liver</strong> <strong>Transplantation: The Recipient.</strong> <strong>33.</strong> Acute Liver Failure and Development of Liver Support Therapy; P. Neuhaus. <strong>34.</strong> Problems of Viral Hepatitis in Liver Transplantation; M.P. Manns, et al. <strong>35.</strong> Rejection and Immunosuppression: Novel Strategies; J. Neuberger. <strong>36.</strong> Liver Transplantation: The Recipient Problems of Anaesthesia; M. Thiel, et al. <strong>37.</strong> Liver Transplantation: The Munich Experience; H.G. Rau, et al. Index.