Preface. Howard Lipton; Forward and acknowledgments Carol Shoshkes Reiss; Part I. RNA Viruses: Introduction Carol Shoshkes Reiss; 1. Neurotropic picornaviruses Vincent Racaniello; 2. Subacute sclerosing panencephalitis James Bale and Robert S. Fujinami; 3. Rabies Monique Lafon; 4. Neurotropic coronavirus infections Stanley Perlman and Noah Butler; 5. Arenavirus infection in the nervous system: uncovering principles of virus-host interaction and viral pathogenesis Stefan Kunz and Juan-Carlos de la Torre; 6. Neurotropic alphaviruses Diane E. Griffin; 7. Flaviviruses Barbara W. Johnson; Part II. Retroviruses, DNA Viruses and Prions: Introduction Carol Shoshkes Reiss; 8. HTLV-1 and disease in the central nervous system Angelina J. Mosley and Charles R. M. Bangham; 9. HIV infection of the central nervous system Iain C. Anthony P Simmonds and J. E. Bell; 10. JC virus molecular biology and the human demyelinating disease, progressive multifocal leukoencephalopathy Kamel Khalili, Mahmut Safak, Luis Del Valle and Martyn K. White; 11. Herpes simplex viruses David C. Bloom and Nicole V. Giordani; 12. Pathogenesis of varicella-zoster virus neurotropism and infection Leigh Zerboni and Ann M. Arvin; 13. Transmissible spongiform encephalopathies Surachai Supattapone and Judy R. Rees; Part III. Immunity, Diagnosis, Vectors and Beneficial Uses of Neurotropic Viruses: Introduction Carol Shoshkes Reiss; 14. Innate immunity in the CNS Carol Shoshkes Reiss; 15. The role of toll like receptors in neurotropic viral infections Robert W. Finberg, Shenghua Zhou and Evelyn A. Kurt-Jones; 16. Neuro-endocrine-immune networks in viral infections C. Jane Welsh, Andrew J. Steelman, Amy N. Sieve, Wentao Mi, Robin R. Johnson, Colin R. Young, Thomas W. Prentice and Mary W. Meagher; 17. Epidemiology of viral encephalitis Nino Khetsuriani and Larry J. Anderson; 18. Pathogen surveillance and discovery W. Ian Lipkin and Thomas Briese; 19. Clinical management of viral encephalitis Kenneth L. Tyler and Don Gilden; 20. Influences of arthropod vectors on encephalitic arboviruses Stephen T. Higgs; 21. The role of bats as reservoir hosts of emerging neurological viruses John S. Mackenzie, James E. Childs, Hume E. Field, Lin-Fa Wang and Andrew C. Breed; 22. Viral oncolysis of glioblastoma William T. Curry, Jr. and Robert L. Martuza; 23. Viral gene therapy for central nervous system disorders Pedro R. Lowenstein, Kurt M. Kroeger and Maria G. Castro.