1. Overview C. Chothia; 2. Picornavirus receptors, tropism and pathogenesis D. J. Evans; 3. Cross-talk between Yersinia and eukaryotic cells G. R. Cornelis; 4. Host-pathogen protein-protein interactions in Staphylococcus T. J. Foster, O. Hartford and D. O'Connell; 5. Mechanisms of microbial adhesion: the paradigm of Neisseriae M. Virji; 6. Virus-host interactions in the control of the gene expression of nuclear replicating DNA viruses R. D. Everett; 7. Regulation of human immunodeficiency virus gene expression Tat J. Karn, N. J. Keen, M. J. Churcher, F Aboul-Ela, G. Varani and M. J. Gait; 8. Chlamydia host and host cell interactions M. Ward; 9. Control of the fimbrial expression by a random genetic switch in Escherichia coli C. J. Dorman, N. C. Nolan and S. G. J. Smith; 10. Virus and the protein synthesis machinery of the cell: Offense, defense and dependence M. B. Matthews; 11. Shigella-induced cytoskeletal reorganisation during host cell invasion G. Tran Van Nhieu, T. Adams, C. Dehio, R. Ménard, A. Skoudy, J. Mounier, R. Hellio, P. Gounon and P. Sansonetti; 12. Transport through plasmodesmata and nuclear pores: cell-to-cell movement of plant viruses and nuclear import of Agrobacterium T-DNA R. Lartey, S. Ghoshroy, J. Sheng and V. Citovsky; 13. Viral cell recognition and entry M. Rossman; 14. Enteropathogenic Escherichia coli and Salmonella species: exploitation of host cells? B. Finlay; 15. Host-viral protein-protein in influenza virus replication P. Palese, P. Wang, T. Wolff and R E O'Neill; 16. Transmissible spongiform encephalopathies and the formation of protease-resistant prion protein B. Caughey; Index.