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Immuno-oncology and Immunotherapy Part F

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2026
ISBN13: 9780443296147
Rubricering
Elsevier Science e druk, 2026 9780443296147
Onderdeel van serie Methods in Cell Biology
€ 201,00
Levertijd ongeveer 8 werkdagen

Samenvatting

Immuno-oncology and immunotherapy, Part F, Volume 201 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including an Evaluation of agents that affect anti-tumor function of CD8+ T cells at activation, Cancer cyro-immunotherapy: Models and methods, Methods for analysis of cancer- and TLS-associated immune infiltrates by multiplex immunofluorescence histology, In-vivo measurement of the extracellular ATP concentration by bio-luminescent probes, and much more.

Additional sections cover the Analysis of the tumor microenvironment using imaging mass cytometry data, Saphenous vein blood collection for different immune analyses of living mice, Use of mouse KO models to validate the specificity of monoclonal antibodies, Imaging mass cytometry to analyze the immune TME, Autoimmune arthritis: Transgenic mouse models and methods, Assessment of human and mouse tumor-antigen specific CD8+ T cells by multimer staining in multiple compartments, and more.

Specificaties

ISBN13:9780443296147
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

1. Generation and functional evaluation of STAb-T cells<br>Luis Alvarez-Vallina<br>2. A syngeneic orthotopic mouse model of metastatic colorectal cancer<br>Christel Devaud<br>3. High-parameter T-cell spectral phospho flow cytometry<br>Joshua Brody and Gvantsa Pantsulaia<br>4. Measuring T-cell/CAR T-cell bystander tumor killing in vitro and in vivo<br>Joshua Brody, Matthew Lin and Daniel Charytonowicz<br>5. Quantification and functional assessment of antigen(-) cancer cell variants<br>Joshua Brody, Gvantsa Pantsulaia, Ivan Odak and Xie Xinping<br>6. T-cell and CAR T-cell Cas9-RNP/nucleofection-mediated gene editing<br>Joshua Brody, Gvantsa Pantsulaia and Moah Sohn<br>7. Peripheral blood mononuclear cell (PBMC)- based functional evaluation of human T cell response to suppressive cells and immune-oncology therapeutics<br>Maria G. Castro, Kaushik Banerjee, Pedro R. Lowenstein, Mahmoud Alghamri, Brandon McClellan and Jorge Peña Agudelo<br>8. Integrative analysis of lung multiparametric flow cytometry data to study immune cell dynamics in tumors<br>Romina Goldszmid and Romina Araya<br>9. Multiparametric staining: Combined application of immunofluorescence and in-situ hybridization<br>Barbara Seliger, Marcus Bauer, Andreas Wilfer, Clara Zöllig and Claudia Wickenhauser<br>10. Extracellular matrix and morphology assessment method on live 3D spheroids of thyroid carcinoma<br>Barbara Seliger, Mario Udinotti, Udo Sieboldts and Christoforos Vaxevanis<br>11. Hema-CRISPR: A clone-based protocol for effective genetic editing of hematopoietic stem cells<br>Barbara Seliger, Christoforos Vaxevanis, Mario Udinotti, Dimitris Kokoretsis, Andreas Wilfer, Marcus Bauer and Claudia Wickenhauser<br>12. Patient-derived models of tumor-immune cell interactions<br>Zlatko Trajanoski<br>13. MDSC isolation from human tumors<br>Viktor Umansky, Feyza Gul Ozbay Kurt and Jochen Utikal<br>14. Extracellular vesicles isolation from human maternal fluids<br>Sheila Spada<br>15. Finding a Needle in a Haystack: Measures of Circulating Tumor DNA (ctDNA) to Guide Treatment Decisions in Oncology<br>Lotze, Michael T, Genia Dubrovsky, Jeff Szymanski, Aadel A. Chaudhuri, Jose Zevallos, Noah Earland, Peter Harris and Pradeep Chauhan
€ 201,00
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        Immuno-oncology and Immunotherapy Part F