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Bradykinin

From Vasodilation to Neuroinflammation

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2025
ISBN13: 9780443289071
Rubricering
Elsevier Science e druk, 2025 9780443289071
€ 197,79
Levertijd ongeveer 8 werkdagen

Samenvatting

Bradykinin: From Vasodilation to Neuroinflammation, the latest release in the Molecular Mediators in Health and Disease series is a comprehensive guide to the multi-functional peptide bradykinin and its impact across the human body. The early chapters provide an overview of the biosynthesis and metabolism of bradykinin, understanding its receptors and signaling pathways, and the therapeutic value of agonists and antagonists for targeting these. This book explores the role of bradykinin in vascular, renal, and brain function, as well as its influence on various conditions and diseases, including inflammation, pain, cardiovascular disease, renal disease, obesity, ischemic stroke, and infectious diseases, including Covid-19.

In addition to its foundational knowledge, the book includes extensive coverage of bradykinin biochemistry and molecular biology. It highlights the therapeutic potential of bradykinin, making it an ideal reference for researchers working in these fields. The book serves as an invaluable resource for understanding the complex roles of bradykinin and its applications in medical research and treatment.

Specificaties

ISBN13:9780443289071
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

1. Introduction to bradykinin<br>Réjean Couture<br>2. Tracing the historical journey: milestones and highlights of bradykinin<br>Réjean Couture, Rahmeh Othman, Sébastien Talbot and Jean-Pierre Girolami<br>3. Kinin receptors and their signaling and regulation<br>Fredrik Leeb-Lundberg<br>4. Animal models for studying bradykinin receptors<br>Leonardo Martin, João Bosco Pesquero and Michael Bader<br>5. Peptide and nonpeptide ligands acting at bradykinin receptors<br>François Marceau, Xavier Charest-Morin and Lajos Gera<br>6. Bradykinin-related peptides and their receptors from nonmammalian vertebrates<br>Haixin Qin and Hang Fai Kwok<br>7. Bradykinin forming pathways and the pathogenesis of hereditary angioedema<br>Allen P. Kaplan<br>8. Bradykinin in ACEI and other drug-induced angioedema<br>Nancy J Brown<br>9. The kinins, a family of bioactive peptides that modulate inflammation<br>Carlos D. Figueroa<br>10. Bradykinin in pain<br>Robson da Costa, Marianne N. Manjavachi, Nara L.M. Quintão and Giselle F. Passos<br>11. Bradykinin in cardiovascular physiology and disease<br>François Alhenc-Gelas, Nadine Bouby and Christine Richer-Giudicelli<br>12. Tissue kallikrein in therapeutic angiogenesis: from basic science to clinical applications<br>Paolo Roberto Madeddu<br>13. Bradykinin in diabetes and obesity<br>Alexandre Budu and Ronaldo Carvalho Araujo<br>14. Bradykinin in ocular health and diseases<br>Menakshi Bhat, Réjean Couture and Elvire Vaucher<br>15. Kinin agonists as a means to increase blood–brain barrier permeability of drugs<br>Juliette Latulippe, David Fortin and Fernand Gobeil<br>16. Bradykinin&rsquo;s role in Alzheimer&rsquo;s: protection or damage?<br>Mariana Toricelli and Hudson Sousa Buck<br>17. Bradykinin receptors in neglected parasitic and viral diseases<br>Julio Scharfstein<br>18. Bradykinin in cancer<br>Gabriela Weirich Neculqueo and Maria Martha Campos
€ 197,79
Levertijd ongeveer 8 werkdagen

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